Prophylactic Negative Pressure Therapy in Reducing the Risk of Sternal Wound Infection after Cardiac Surgery

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F25%3A10506754" target="_blank" >RIV/00179906:_____/25:10506754 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/25:10506754

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=DI2eNLcEY8" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=DI2eNLcEY8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33678/cor.2025.030" target="_blank" >10.33678/cor.2025.030</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prophylactic Negative Pressure Therapy in Reducing the Risk of Sternal Wound Infection after Cardiac Surgery

Popis výsledku v původním jazyce

Background: Postoperative sternal wound infections and dehiscence are serious complications of cardiac surgery that increase the length of hospital stay and healthcare costs. Standard wound care may be insufficient for preventing these complications in high-risk patients. Methods: We conducted a prospective, randomized study comparing the efficacy of closed incisional negative pressure wound therapy (ciNPWT) using Prevena (study group) versus standard wound dressing (control group) in patients at high risk of sternal wound infections following cardiac surgery. Primary outcomes included the incidence of sternal wound infection at seven days and three months postoperatively, and length of hospital stay. Results: The study cohort comprised 80 patients (64 male, 16 female; mean age 65.4 years) randomized into two groups with 40 patients in each. At 7 days post-operation, there were four patients with sternal wound infection in the study group (10 %) and seven in the control group (17.5%) (p-value=0.52). At 3 months, deep wound infections were present in 1 patient in the study group (2.5%) and 2 in the control group (5%) (p = 1.00). Median length of hospital stay was comparable between the study (12 days) and control (11 days) groups (p-value = 0.75). Conclusions: Preventive negative pressure wound treatment showed a trend towards reducing the incidence of wound healing complications in high-risk patients following cardiac surgery, although the differences were not statistically significant. Further large-scale studies are warranted to establish the efficacy and cost--effectiveness of this preventive strategy.

Název v anglickém jazyce

Prophylactic Negative Pressure Therapy in Reducing the Risk of Sternal Wound Infection after Cardiac Surgery

Popis výsledku anglicky

Background: Postoperative sternal wound infections and dehiscence are serious complications of cardiac surgery that increase the length of hospital stay and healthcare costs. Standard wound care may be insufficient for preventing these complications in high-risk patients. Methods: We conducted a prospective, randomized study comparing the efficacy of closed incisional negative pressure wound therapy (ciNPWT) using Prevena (study group) versus standard wound dressing (control group) in patients at high risk of sternal wound infections following cardiac surgery. Primary outcomes included the incidence of sternal wound infection at seven days and three months postoperatively, and length of hospital stay. Results: The study cohort comprised 80 patients (64 male, 16 female; mean age 65.4 years) randomized into two groups with 40 patients in each. At 7 days post-operation, there were four patients with sternal wound infection in the study group (10 %) and seven in the control group (17.5%) (p-value=0.52). At 3 months, deep wound infections were present in 1 patient in the study group (2.5%) and 2 in the control group (5%) (p = 1.00). Median length of hospital stay was comparable between the study (12 days) and control (11 days) groups (p-value = 0.75). Conclusions: Preventive negative pressure wound treatment showed a trend towards reducing the incidence of wound healing complications in high-risk patients following cardiac surgery, although the differences were not statistically significant. Further large-scale studies are warranted to establish the efficacy and cost--effectiveness of this preventive strategy.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cor et Vasa

ISSN

0010-8650

e-ISSN

1803-7712

Svazek periodika

67

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

572-575

Kód UT WoS článku

001618286800003

EID výsledku v databázi Scopus

2-s2.0-105023961653