Self-reported history of infections and the risk of non-Hodgkin lymphoma: an InterLymph pooled analysis

Kód výsledku v IS VaVaI

RIV/00209805:_____/12:#0000346 - isvavai.cz

Výsledek na webu

http://onlinelibrary.wiley.com/doi/10.1002/ijc.27438/abstract;jsessionid=345264F4D0E6A52A5FD7FE989270EBE4.d03t01

DOI - Digital Object Identifier

10.1002/ijc.27438

Jazyk výsledku

angličtina

Název v původním jazyce

Self-reported history of infections and the risk of non-Hodgkin lymphoma: an InterLymph pooled analysis

Popis výsledku v původním jazyce

We performed a pooled analysis of data on self-reported history of infections in relation to the risk of non-Hodgkin lymphoma (NHL) from 17 casecontrol studies that included 12,585 cases and 15,416 controls aged 1696 years at recruitment. Pooled odds ratios (OR) and 95% confidence intervals (95% CI) were estimated in two-stage random-effect or joint fixed-effect models, adjusting for age, sex and study centre. Data from the 2 years before diagnosis (or date of interview for controls) were excluded. A self-reported history of infectious mononucleosis was associated with an excess risk of NHL (OR = 1.26, 95% CI = 1.011.57 based on data from 16 studies); study-specific results indicate significant (I2 = 51%, p = 0.01) heterogeneity. A self-reported history of measles or whooping cough was associated with an approximate 15% reduction in risk. History of other infection was not associated with NHL. We find little clear evidence of an association between NHL risk and infection although the l

Název v anglickém jazyce

Self-reported history of infections and the risk of non-Hodgkin lymphoma: an InterLymph pooled analysis

Popis výsledku anglicky

We performed a pooled analysis of data on self-reported history of infections in relation to the risk of non-Hodgkin lymphoma (NHL) from 17 casecontrol studies that included 12,585 cases and 15,416 controls aged 1696 years at recruitment. Pooled odds ratios (OR) and 95% confidence intervals (95% CI) were estimated in two-stage random-effect or joint fixed-effect models, adjusting for age, sex and study centre. Data from the 2 years before diagnosis (or date of interview for controls) were excluded. A self-reported history of infectious mononucleosis was associated with an excess risk of NHL (OR = 1.26, 95% CI = 1.011.57 based on data from 16 studies); study-specific results indicate significant (I2 = 51%, p = 0.01) heterogeneity. A self-reported history of measles or whooping cough was associated with an approximate 15% reduction in risk. History of other infection was not associated with NHL. We find little clear evidence of an association between NHL risk and infection although the l

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International journal of cancer

ISSN

0020-7136

e-ISSN

—

Svazek periodika

131

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

2342-2348

Kód UT WoS článku

000309185300015

EID výsledku v databázi Scopus

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