A simple model to assess the probability of invasion in ductal carcinoma in situ of the breast diagnosed by needle biopsy

Kód výsledku v IS VaVaI

RIV/00209805:_____/14:#0000558 - isvavai.cz

Nalezeny alternativní kódy

RIV/00216224:14310/14:00082123

Výsledek na webu

http://dx.doi.org/10.1155/2014/480840

DOI - Digital Object Identifier

10.1155/2014/480840

Jazyk výsledku

angličtina

Název v původním jazyce

A simple model to assess the probability of invasion in ductal carcinoma in situ of the breast diagnosed by needle biopsy

Popis výsledku v původním jazyce

The aim of the study was to develop a clinical prediction model for assessing the probability of having invasive cancer in the definitive surgical resection specimen in patients with biopsy diagnosis of ductal carcinoma in situ (DCIS) of the breast, to facilitate decision making regarding axillary surgery. Methods. In 349 women with DCIS, predictors of invasion in the definitive resection specimen were identified. A model to predict the probability of invasion was developed and subsequently simplified to divide patients into two risk categories. The model?s performance was validated on another patient population. Multivariate logistic regression revealed four independent predictors of invasion: (i) suspicious (micro)invasion in the biopsy specimen; (ii) visibility of the lesion on ultrasonography; (iii) size of the lesion on mammography >30 mm;(iv) clinical palpability of the lesion.The actual frequency of invasion in the high-risk patient group in the test and validation population wa

Název v anglickém jazyce

A simple model to assess the probability of invasion in ductal carcinoma in situ of the breast diagnosed by needle biopsy

Popis výsledku anglicky

The aim of the study was to develop a clinical prediction model for assessing the probability of having invasive cancer in the definitive surgical resection specimen in patients with biopsy diagnosis of ductal carcinoma in situ (DCIS) of the breast, to facilitate decision making regarding axillary surgery. Methods. In 349 women with DCIS, predictors of invasion in the definitive resection specimen were identified. A model to predict the probability of invasion was developed and subsequently simplified to divide patients into two risk categories. The model?s performance was validated on another patient population. Multivariate logistic regression revealed four independent predictors of invasion: (i) suspicious (micro)invasion in the biopsy specimen; (ii) visibility of the lesion on ultrasonography; (iii) size of the lesion on mammography >30 mm;(iv) clinical palpability of the lesion.The actual frequency of invasion in the high-risk patient group in the test and validation population wa

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

ED2.1.00/03.0101: Regionální centrum aplikované molekulární onkologie (RECAMO)

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BioMed research international

ISSN

2314-6133

e-ISSN

—

Svazek periodika

2014

Číslo periodika v rámci svazku

8 July

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

480840

Kód UT WoS článku

000339252800001

EID výsledku v databázi Scopus

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