Sex differences in the incidence trends of early-onset gastrointestinal cancer - the European/Mediterranean perspective

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F25%3A00080512" target="_blank" >RIV/00209805:_____/25:00080512 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/25:00143803

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S2949819825001074" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2949819825001074</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.esmogo.2025.100238" target="_blank" >10.1016/j.esmogo.2025.100238</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Sex differences in the incidence trends of early-onset gastrointestinal cancer - the European/Mediterranean perspective

Popis výsledku v původním jazyce

BackgroundWhile the rising incidence of early-onset colorectal cancer has been documented worldwide, there is a paucity of data on the epidemiological changes in other gastrointestinal (GI) cancers in the young population in Europe. We sought to characterize incidence patterns of GI cancers in young patients in different European/Mediterranean countries.Patients and methodsNational cancer registries in several European countries were contacted to obtain the absolute number of GI cancer cases per age group (15-49 years) at 5-year intervals and the absolute population size for each of these age groups annually from 2008 to 2018. Data were analyzed to calculate year-to-year incidence rate change and average annual percentage change.ResultsSeven countries were included in the analysis: the Czech Republic, Germany, Israel, the Netherlands, Norway, Slovenia, and Spain. Different trends were observed for different GI cancers. For colorectal cancer, all countries except Germany showed increasing incidence rates in a similar pattern for males and females. An increasing trend in pancreatic cancer was documented in the Czech Republic, more in males, and in Slovenia and Israel significantly more in females. There was a slight increase in Spain and Germany, with no difference by sex. The incidence of early-onset gastric and esophageal cancer was very low and non-rising.ConclusionsEarly-onset cancers along the GI tract show different patterns in different European countries. For some types of GI tumors the incidence was fairly stable between 2008 and 2018 while some were increasing, in particular colorectal cancer in both sexes, and pancreatic cancer in females.

Název v anglickém jazyce

Sex differences in the incidence trends of early-onset gastrointestinal cancer - the European/Mediterranean perspective

Popis výsledku anglicky

BackgroundWhile the rising incidence of early-onset colorectal cancer has been documented worldwide, there is a paucity of data on the epidemiological changes in other gastrointestinal (GI) cancers in the young population in Europe. We sought to characterize incidence patterns of GI cancers in young patients in different European/Mediterranean countries.Patients and methodsNational cancer registries in several European countries were contacted to obtain the absolute number of GI cancer cases per age group (15-49 years) at 5-year intervals and the absolute population size for each of these age groups annually from 2008 to 2018. Data were analyzed to calculate year-to-year incidence rate change and average annual percentage change.ResultsSeven countries were included in the analysis: the Czech Republic, Germany, Israel, the Netherlands, Norway, Slovenia, and Spain. Different trends were observed for different GI cancers. For colorectal cancer, all countries except Germany showed increasing incidence rates in a similar pattern for males and females. An increasing trend in pancreatic cancer was documented in the Czech Republic, more in males, and in Slovenia and Israel significantly more in females. There was a slight increase in Spain and Germany, with no difference by sex. The incidence of early-onset gastric and esophageal cancer was very low and non-rising.ConclusionsEarly-onset cancers along the GI tract show different patterns in different European countries. For some types of GI tumors the incidence was fairly stable between 2008 and 2018 while some were increasing, in particular colorectal cancer in both sexes, and pancreatic cancer in females.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ESMO Gastrointestinal Oncology

ISSN

2949-8198

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

December 2025

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

100238

Kód UT WoS článku

001633891600003

EID výsledku v databázi Scopus

2-s2.0-105015784373