Two-year follow-up of two patients after severe thallium intoxication

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F09%3A4367" target="_blank" >RIV/00216208:11110/09:4367 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/09:4367

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Two-year follow-up of two patients after severe thallium intoxication

Popis výsledku v původním jazyce

We report two patients who were repeatedly exposed to thallium poisoning experienced hair loss, polyneuropathy, and visual impairment. Nerve conduction studies (NCSs), visual evoked potentials (VEP), brainstem auditory evoked potentials (BAEP) changes, and optical neuropathy developed within a few months latency after the first subjective signs. Thallium poisoning was confirmed by toxicological analysis of blood and/or urine and feces in both the patients and in the microscopic hair analysis of the daughter. Both patients were treated with Prussian blue. The hair loss was fully reversible. During a 2-year follow-up after the poisoning, polpolyneuropathy in the lower extremities improved substantially. Additionally, severe asymmetrical vision impairmentpersists in both women, with central scotomata and impaired color discrimination in both eyes. Substantial improvement of their visual function is unlikely.

Název v anglickém jazyce

Two-year follow-up of two patients after severe thallium intoxication

Popis výsledku anglicky

We report two patients who were repeatedly exposed to thallium poisoning experienced hair loss, polyneuropathy, and visual impairment. Nerve conduction studies (NCSs), visual evoked potentials (VEP), brainstem auditory evoked potentials (BAEP) changes, and optical neuropathy developed within a few months latency after the first subjective signs. Thallium poisoning was confirmed by toxicological analysis of blood and/or urine and feces in both the patients and in the microscopic hair analysis of the daughter. Both patients were treated with Prussian blue. The hair loss was fully reversible. During a 2-year follow-up after the poisoning, polpolyneuropathy in the lower extremities improved substantially. Additionally, severe asymmetrical vision impairmentpersists in both women, with central scotomata and impaired color discrimination in both eyes. Substantial improvement of their visual function is unlikely.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Human & Experimental Toxicology

ISSN

0960-3271

e-ISSN

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Svazek periodika

28

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

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Kód UT WoS článku

000269819900002

EID výsledku v databázi Scopus

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