The Effect of Pheochromocytoma Treatment on Subclinical Inflammation and Endocrine Function of Adipose Tissue

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F09%3A4640" target="_blank" >RIV/00216208:11110/09:4640 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/09:4640

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The Effect of Pheochromocytoma Treatment on Subclinical Inflammation and Endocrine Function of Adipose Tissue

Popis výsledku v původním jazyce

The aim of our study was to evaluate the influence of surgical removal of pheochromocytoma on the endocrine function of adipose tissue and subclinical inflammation as measured by circulating C-reactive protein (CRP) levels. Eighteen patients with newly diagnosed pheochromocytoma were included into study. Anthropometric measures, biochemical parameters, serum CRP, leptin, adiponectin and resistin levels were measured at the time of diagnosis and six months after surgical removal of pheochromocytoma. Surgical removal of pheochromocytoma significantly increased body weight, decreased BP, fasting blood glucose and glycated hemoglobin levels. Serum CRP levels were decreased by 50% six months after surgical removal(p<0.05) despite a significant increase in body weight. Serum leptin, adiponectin and resistin levels were not affected by the surgery.

Název v anglickém jazyce

The Effect of Pheochromocytoma Treatment on Subclinical Inflammation and Endocrine Function of Adipose Tissue

Popis výsledku anglicky

The aim of our study was to evaluate the influence of surgical removal of pheochromocytoma on the endocrine function of adipose tissue and subclinical inflammation as measured by circulating C-reactive protein (CRP) levels. Eighteen patients with newly diagnosed pheochromocytoma were included into study. Anthropometric measures, biochemical parameters, serum CRP, leptin, adiponectin and resistin levels were measured at the time of diagnosis and six months after surgical removal of pheochromocytoma. Surgical removal of pheochromocytoma significantly increased body weight, decreased BP, fasting blood glucose and glycated hemoglobin levels. Serum CRP levels were decreased by 50% six months after surgical removal(p<0.05) despite a significant increase in body weight. Serum leptin, adiponectin and resistin levels were not affected by the surgery.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

<a href="/cs/project/NR8302" target="_blank" >NR8302: VÝZNAM A MECHANIZMUS PŮSOBENÍ ADIPOCYTÁRNÍCH HORMONŮ PŘI REGULACI INZULÍNOVÉ SENZITIVITY U PACIENTEK S INZULÍNOVOU REZISTENCÍ RŮZNÉ ETIOLOGIE</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological Research

ISSN

0862-8408

e-ISSN

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Svazek periodika

58

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

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Kód UT WoS článku

000268125600002

EID výsledku v databázi Scopus

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