Clinical features of childhood narcolepsy. Can cataplexy be foretold?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A8887" target="_blank" >RIV/00216208:11110/11:8887 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023001:_____/11:00002476 RIV/00064165:_____/11:8887

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ejpn.2011.01.008" target="_blank" >http://dx.doi.org/10.1016/j.ejpn.2011.01.008</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Clinical features of childhood narcolepsy. Can cataplexy be foretold?

Popis výsledku v původním jazyce

The aim of our study was to evaluate clinical and polysomnographic parameters to verify if cataplexy appearing later in life can be foretold. Methods: 30 patients (12 boys), who contracted narcolepsy before the age of 18, were enrolled. All underwent clinical examination, nocturnal polysomnography (PSG), multiple sleep latency test (MSLT), HLA-DQB1*0602 testing and, most of them Epworth Sleepiness Scale (ESS) rating. The Mann Whitney rank and Fisher's tests were used for statistical analysis. Results: Narcolepsy without cataplexy (NwC) was diagnosed in 40% of the patients. The mean age at the first symptoms was 14.0 +/- 3.0, at diagnosis 15.6 +/- 3.1 years. Narcolepsy was accompanied by hypnagogic hallucinations in 15 and sleep paralysis in 12 patients. Conclusion: Narcolepsy in childhood leaves very little scope for the prediction of cataplexy later in life.

Název v anglickém jazyce

Clinical features of childhood narcolepsy. Can cataplexy be foretold?

Popis výsledku anglicky

The aim of our study was to evaluate clinical and polysomnographic parameters to verify if cataplexy appearing later in life can be foretold. Methods: 30 patients (12 boys), who contracted narcolepsy before the age of 18, were enrolled. All underwent clinical examination, nocturnal polysomnography (PSG), multiple sleep latency test (MSLT), HLA-DQB1*0602 testing and, most of them Epworth Sleepiness Scale (ESS) rating. The Mann Whitney rank and Fisher's tests were used for statistical analysis. Results: Narcolepsy without cataplexy (NwC) was diagnosed in 40% of the patients. The mean age at the first symptoms was 14.0 +/- 3.0, at diagnosis 15.6 +/- 3.1 years. Narcolepsy was accompanied by hypnagogic hallucinations in 15 and sleep paralysis in 12 patients. Conclusion: Narcolepsy in childhood leaves very little scope for the prediction of cataplexy later in life.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Paediatric Neurology

ISSN

1090-3798

e-ISSN

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Svazek periodika

15

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

320-325

Kód UT WoS článku

000296670400007

EID výsledku v databázi Scopus

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