Associations of Serum Levels of Advanced Glycation end Products with Nutrition Markers and Anemia in Patients with Chronic Kidney Disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9162" target="_blank" >RIV/00216208:11110/11:9162 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21230/11:00184514 RIV/00064165:_____/11:9162

Výsledek na webu

<a href="http://dx.doi.org/10.3109/0886022X.2010.541581" target="_blank" >http://dx.doi.org/10.3109/0886022X.2010.541581</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Associations of Serum Levels of Advanced Glycation end Products with Nutrition Markers and Anemia in Patients with Chronic Kidney Disease

Popis výsledku v původním jazyce

Background: Advanced glycation end product (AGE) levels are elevated in patients with decreased renal function and may contribute to the excessive cardiovascular disease in this population. However, their relation to nutrition, anemia, and micro inflammation is not well characterized. The aim of this study is to determine their relationship in patients with chronic kidney disease (CKD). Methods: The studied group consisted of 203 subjects: 159 patients with CKD 1--5 and 44 healthy control subjects. AGElevels were assessed by spectrofluorimetry, and routine biochemical parameters were measured using standard methods. Results: AGE levels were significantly increased in CKD patients compared with controls (3.9 +/-+/- 1.7 xx 105 AU in CKD 1--5 patients vs. 3.2 +/-+/- 0.48 xx 105 AU in controls, p < 0.0001). AGE levels increased from CKD 3. AGE levels were positively associated with age, albumin, prealbumin, and orosomucoid, and were negatively associated with hemoglobin and estimated glom

Název v anglickém jazyce

Associations of Serum Levels of Advanced Glycation end Products with Nutrition Markers and Anemia in Patients with Chronic Kidney Disease

Popis výsledku anglicky

Background: Advanced glycation end product (AGE) levels are elevated in patients with decreased renal function and may contribute to the excessive cardiovascular disease in this population. However, their relation to nutrition, anemia, and micro inflammation is not well characterized. The aim of this study is to determine their relationship in patients with chronic kidney disease (CKD). Methods: The studied group consisted of 203 subjects: 159 patients with CKD 1--5 and 44 healthy control subjects. AGElevels were assessed by spectrofluorimetry, and routine biochemical parameters were measured using standard methods. Results: AGE levels were significantly increased in CKD patients compared with controls (3.9 +/-+/- 1.7 xx 105 AU in CKD 1--5 patients vs. 3.2 +/-+/- 0.48 xx 105 AU in controls, p < 0.0001). AGE levels increased from CKD 3. AGE levels were positively associated with age, albumin, prealbumin, and orosomucoid, and were negatively associated with hemoglobin and estimated glom

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Renal Failure

ISSN

0886-022X

e-ISSN

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Svazek periodika

33

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

131-137

Kód UT WoS článku

000287485800004

EID výsledku v databázi Scopus

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