Coupled expression of dipeptidyl peptidase-IV and fibroblast activation protein-alpha in transformed astrocytic cells

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9956" target="_blank" >RIV/00216208:11110/11:9956 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/11:9956

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11010-011-0828-z" target="_blank" >http://dx.doi.org/10.1007/s11010-011-0828-z</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Coupled expression of dipeptidyl peptidase-IV and fibroblast activation protein-alpha in transformed astrocytic cells

Popis výsledku v původním jazyce

Dipeptidyl peptidase-IV (DPP-IV) and Fibroblast activation protein-a (FAP) are speculated to participate in the regulation of multiple biological processes. The role of DPP-IV and FAP in the development and progression of various types of tumours, including glioblastoma, is intensively studied and their functional crosstalk is hypothesized. Here we describe the correlative expression of DPP-IV and FAP mRNA in primary cell cultures derived from human glioblastoma and associated expression dynamics of both molecules in astrocytoma cell lines depending on culture conditions. Understanding of the expressional and functional coordination of DPP-IV and FAP may help clarify the mechanisms of biological roles of both molecules in transformed astrocytic cells.

Název v anglickém jazyce

Coupled expression of dipeptidyl peptidase-IV and fibroblast activation protein-alpha in transformed astrocytic cells

Popis výsledku anglicky

Dipeptidyl peptidase-IV (DPP-IV) and Fibroblast activation protein-a (FAP) are speculated to participate in the regulation of multiple biological processes. The role of DPP-IV and FAP in the development and progression of various types of tumours, including glioblastoma, is intensively studied and their functional crosstalk is hypothesized. Here we describe the correlative expression of DPP-IV and FAP mRNA in primary cell cultures derived from human glioblastoma and associated expression dynamics of both molecules in astrocytoma cell lines depending on culture conditions. Understanding of the expressional and functional coordination of DPP-IV and FAP may help clarify the mechanisms of biological roles of both molecules in transformed astrocytic cells.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Molecular and Cellular Biochemistry

ISSN

0300-8177

e-ISSN

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Svazek periodika

354

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

283-289

Kód UT WoS článku

000292215600030

EID výsledku v databázi Scopus

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