Disturbance of real space navigation in moderately advanced but not in early Huntington's disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11918" target="_blank" >RIV/00216208:11110/12:11918 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/12:8035 RIV/00159816:_____/12:#0001019 RIV/00064203:_____/12:8035 RIV/00064165:_____/12:11918

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jns.2011.08.016" target="_blank" >http://dx.doi.org/10.1016/j.jns.2011.08.016</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Disturbance of real space navigation in moderately advanced but not in early Huntington's disease

Popis výsledku v původním jazyce

Background: Visuospatial skills including spatial navigation are known to be impaired in Huntington's disease. Spatial navigation comprises two navigational frameworks, allocentric and egocentric. Several studies have associated the allocentric navigation with the hippocampus and the egocentric navigation with the striatum. The striatum is predominantly impaired from the early stages of Huntington's disease. Objective: To find whether spatial navigation impairment is present in the early stages of Huntington's disease and to test the hypothesis that the egocentric navigation is predominantly affected compared to the allocentric navigation. Methods: In nineteen patients with Huntington's disease the egocentric and the allocentric navigation skills weretested using the Blue Velvet Arena, a human analog of Morris Water Maze, and compared to nineteen age and gender-matched healthy controls. Cognitive functions, with emphasis on the executive functions, were also assessed. Results: The spa

Název v anglickém jazyce

Disturbance of real space navigation in moderately advanced but not in early Huntington's disease

Popis výsledku anglicky

Background: Visuospatial skills including spatial navigation are known to be impaired in Huntington's disease. Spatial navigation comprises two navigational frameworks, allocentric and egocentric. Several studies have associated the allocentric navigation with the hippocampus and the egocentric navigation with the striatum. The striatum is predominantly impaired from the early stages of Huntington's disease. Objective: To find whether spatial navigation impairment is present in the early stages of Huntington's disease and to test the hypothesis that the egocentric navigation is predominantly affected compared to the allocentric navigation. Methods: In nineteen patients with Huntington's disease the egocentric and the allocentric navigation skills weretested using the Blue Velvet Arena, a human analog of Morris Water Maze, and compared to nineteen age and gender-matched healthy controls. Cognitive functions, with emphasis on the executive functions, were also assessed. Results: The spa

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the Neurological Sciences

ISSN

0022-510X

e-ISSN

—

Svazek periodika

312

Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

86-91

Kód UT WoS článku

000299446200018

EID výsledku v databázi Scopus

—