Primary Synovial Sarcoma of the Uterus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12400" target="_blank" >RIV/00216208:11110/12:12400 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/12:12400

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s12253-011-9391-x" target="_blank" >http://dx.doi.org/10.1007/s12253-011-9391-x</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Primary Synovial Sarcoma of the Uterus

Popis výsledku v původním jazyce

We report a case of a 52-year-old female with synovial sarcoma of the uterine corpus. Grossly, the partly polypoid tumor involved the endometrium with invasion into the inner half of the myometrium. Histologically, the tumor showed biphasic structure with the predominance of poorly differentiated small to medium sized round to oval cells. These cells showed high nuclear to cytoplasmic ratio and were arranged in diffuse sheets. Other component consisted of larger epitheloid cells with ample eosinophiliccytoplasm arranged in irregular nests. These cells were only present in a small amount. Immunohistochemically, the tumor cells in both components showed the expression of EMA, S-100 protein, CD99, and NSE. RT-PCR analysis showed the presence of SYT-SSX1fusion transcript. At present, the patient shows no signs of tumor relapse 56 months after the diagnosis. To the best of our knowledge, this is the first report of synovial sarcoma arising in uterus.

Název v anglickém jazyce

Primary Synovial Sarcoma of the Uterus

Popis výsledku anglicky

We report a case of a 52-year-old female with synovial sarcoma of the uterine corpus. Grossly, the partly polypoid tumor involved the endometrium with invasion into the inner half of the myometrium. Histologically, the tumor showed biphasic structure with the predominance of poorly differentiated small to medium sized round to oval cells. These cells showed high nuclear to cytoplasmic ratio and were arranged in diffuse sheets. Other component consisted of larger epitheloid cells with ample eosinophiliccytoplasm arranged in irregular nests. These cells were only present in a small amount. Immunohistochemically, the tumor cells in both components showed the expression of EMA, S-100 protein, CD99, and NSE. RT-PCR analysis showed the presence of SYT-SSX1fusion transcript. At present, the patient shows no signs of tumor relapse 56 months after the diagnosis. To the best of our knowledge, this is the first report of synovial sarcoma arising in uterus.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Pathology and Oncology Research

ISSN

1219-4956

e-ISSN

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Svazek periodika

18

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

HU - Maďarsko

Počet stran výsledku

5

Strana od-do

529-533

Kód UT WoS článku

000303538200051

EID výsledku v databázi Scopus

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