Is age a risk factor for hypothyroidism in pregnancy? An analysis of 5223 pregnant women

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12530" target="_blank" >RIV/00216208:11110/12:12530 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61384399:31130/12:00038867 RIV/00064165:_____/12:12530

Výsledek na webu

<a href="http://dx.doi.org/10.1210/jc.2011-3275" target="_blank" >http://dx.doi.org/10.1210/jc.2011-3275</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Is age a risk factor for hypothyroidism in pregnancy? An analysis of 5223 pregnant women

Popis výsledku v původním jazyce

Context: The guidelines of American Thyroid Association from 2011 include age over 30 as one of the risk factors for hypothyroidism in pregnancy. Objective: Our objective was to verify whether age increases the risk of autoimmune thyroid disease in pregnancy. Design: We performed a cross-sectional study in 2006-2008 with laboratory assessment in a single center using primary care gynecological ambulances in cooperation with a referral center. Patients: The study included 5223 consecutive pregnant womenin gestational wk 9-12. Main Outcome Measure: Weassessed the occurrence of pathological serum concentrations of TSH and/ or antibodies against thyroperoxidase (TPOAb) with regard to age. Reference interval for TSH was 0.06-3.67 mU/liter; the upper cutoffvalue for TPOAb was 143 kU/liter. Results: Overall, 857 women (16.4%) were positively screened. Of these, 294 (5.63%) had TSH elevation, 146 (2.79%) had TSH suppression, 561 (10.74%) were TPOAb positive, and 417 (7.98%) were euthyroid an

Název v anglickém jazyce

Is age a risk factor for hypothyroidism in pregnancy? An analysis of 5223 pregnant women

Popis výsledku anglicky

Context: The guidelines of American Thyroid Association from 2011 include age over 30 as one of the risk factors for hypothyroidism in pregnancy. Objective: Our objective was to verify whether age increases the risk of autoimmune thyroid disease in pregnancy. Design: We performed a cross-sectional study in 2006-2008 with laboratory assessment in a single center using primary care gynecological ambulances in cooperation with a referral center. Patients: The study included 5223 consecutive pregnant womenin gestational wk 9-12. Main Outcome Measure: Weassessed the occurrence of pathological serum concentrations of TSH and/ or antibodies against thyroperoxidase (TPOAb) with regard to age. Reference interval for TSH was 0.06-3.67 mU/liter; the upper cutoffvalue for TPOAb was 143 kU/liter. Results: Overall, 857 women (16.4%) were positively screened. Of these, 294 (5.63%) had TSH elevation, 146 (2.79%) had TSH suppression, 561 (10.74%) were TPOAb positive, and 417 (7.98%) were euthyroid an

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

<a href="/cs/project/NS10662" target="_blank" >NS10662: Komplement v etiopatogenezi autoimunitních tyreopatií</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Clinical Endocrinology and Metabolism

ISSN

0021-972X

e-ISSN

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Svazek periodika

97

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

1945-1952

Kód UT WoS článku

000306100800045

EID výsledku v databázi Scopus

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