Disseminated and Circulating Tumour Cells and Their Role in Breast Cancer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12957" target="_blank" >RIV/00216208:11110/12:12957 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/12:12957

Výsledek na webu

<a href="http://fb.cuni.cz/file/5642/FB2012A0015.pdf" target="_blank" >http://fb.cuni.cz/file/5642/FB2012A0015.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Disseminated and Circulating Tumour Cells and Their Role in Breast Cancer

Popis výsledku v původním jazyce

Metastatic spread of the primary tumour is responsible for the vast majority of cancer-related deaths. Detection of disseminated tumour cells in the bone marrow and circulating tumour cells in the peripheral blood is correlated with early metastatic relapse in breast cancer. Positive detection of disseminated tumour cells was associated with poor overall survival of patients. Current research has been focused on integrating minimal residual disease as a prognostic and predictive tool in the management of breast cancer. Detection of disseminated tumour cells/circulating tumour cells is not yet standardized in clinical practice because of using different enrichment and detection methods. Therefore, standardization of the used methods is necessary in thefuture. Previous achieved findings must be verified in larger prospective multicentre studies. Further characterization of disseminated tumour cells/circulating tumour cells will be essential for developing and monitoring the efficacy of

Název v anglickém jazyce

Disseminated and Circulating Tumour Cells and Their Role in Breast Cancer

Popis výsledku anglicky

Metastatic spread of the primary tumour is responsible for the vast majority of cancer-related deaths. Detection of disseminated tumour cells in the bone marrow and circulating tumour cells in the peripheral blood is correlated with early metastatic relapse in breast cancer. Positive detection of disseminated tumour cells was associated with poor overall survival of patients. Current research has been focused on integrating minimal residual disease as a prognostic and predictive tool in the management of breast cancer. Detection of disseminated tumour cells/circulating tumour cells is not yet standardized in clinical practice because of using different enrichment and detection methods. Therefore, standardization of the used methods is necessary in thefuture. Previous achieved findings must be verified in larger prospective multicentre studies. Further characterization of disseminated tumour cells/circulating tumour cells will be essential for developing and monitoring the efficacy of

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Folia Biologica

ISSN

0015-5500

e-ISSN

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Svazek periodika

58

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

11

Strana od-do

87-97

Kód UT WoS článku

000306098400001

EID výsledku v databázi Scopus

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