Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A9949" target="_blank" >RIV/00216208:11110/12:9949 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/12:9949

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00415-011-6323-3" target="_blank" >http://dx.doi.org/10.1007/s00415-011-6323-3</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor

Popis výsledku v původním jazyce

Ethanol is known to improve tremor in a proportion of patients with essential tremor. Increased incidence of alcoholism has been suspected in essential tremor patients; however, no objective evaluation has been performed using laboratory markers to date.Data on alcohol intake in the last 30 days were acquired in 95 essential tremor patients and 35 healthy controls. Blood and urine markers related to alcohol metabolism and liver function were evaluated. Self-reported alcohol intake and biomarker levelswere higher in essential tremor, but the difference was only significant for carbohydrate-deficient transferrin. None of the subjects presented with laboratory parameters reflecting chronic alcohol abuse. Our data do not reflect a higher incidence of alcoholism in patients with essential tremor. Their alcohol intake is well controlled and does not exceed the limits of healthy social drinking.

Název v anglickém jazyce

Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor

Popis výsledku anglicky

Ethanol is known to improve tremor in a proportion of patients with essential tremor. Increased incidence of alcoholism has been suspected in essential tremor patients; however, no objective evaluation has been performed using laboratory markers to date.Data on alcohol intake in the last 30 days were acquired in 95 essential tremor patients and 35 healthy controls. Blood and urine markers related to alcohol metabolism and liver function were evaluated. Self-reported alcohol intake and biomarker levelswere higher in essential tremor, but the difference was only significant for carbohydrate-deficient transferrin. None of the subjects presented with laboratory parameters reflecting chronic alcohol abuse. Our data do not reflect a higher incidence of alcoholism in patients with essential tremor. Their alcohol intake is well controlled and does not exceed the limits of healthy social drinking.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/NS10336" target="_blank" >NS10336: Poruchy stability a chůze u Parkinsonovy nemoci a jiných neurodegenerativních onemocnění s projevy parkinsonského syndromu - analýza mechanismů a rizik pádů a vývoj rehabilitačního programu pro jejich prevenci</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Neurology

ISSN

0340-5354

e-ISSN

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Svazek periodika

259

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

4

Strana od-do

1177-1180

Kód UT WoS článku

000304859300023

EID výsledku v databázi Scopus

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