Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10188935" target="_blank" >RIV/00216208:11110/13:10188935 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216275:25520/13:39896437 RIV/00064203:_____/13:10188935 RIV/00064165:_____/13:10188935

Výsledek na webu

<a href="http://dx.doi.org/10.1002/mus.23657" target="_blank" >http://dx.doi.org/10.1002/mus.23657</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/mus.23657" target="_blank" >10.1002/mus.23657</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome

Popis výsledku v původním jazyce

Introduction: Myasthenia gravis is an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non-cancerous angiofolicular hyperplasia of lymphatic tissue. Methods and results: We describe a young man with rapid, successive manifestations of myasthenia gravis, a solitary form of Castleman disease, pemphigus vulgaris, and anti-phospholipid syndrome, which resulted in 2 ischemic cerebrovascularevents that caused a severe central neurological deficit. Discussion: We were unable to find a similar case in the literature, but we hypothesize that the temporal concidence of these clinical entities may be related to a common immunological pathway, such as B-cell activation. Therefore, we treated the patient with an immunosuppressant and anticoagulant treatment, as well as rituximab, a monoclonal antibody therapy against CD20+. Muscle Nerve 47:447-451, 2013

Název v anglickém jazyce

Myasthenia gravis, castleman disease, pemphigus, and anti-phospholipid syndrome

Popis výsledku anglicky

Introduction: Myasthenia gravis is an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non-cancerous angiofolicular hyperplasia of lymphatic tissue. Methods and results: We describe a young man with rapid, successive manifestations of myasthenia gravis, a solitary form of Castleman disease, pemphigus vulgaris, and anti-phospholipid syndrome, which resulted in 2 ischemic cerebrovascularevents that caused a severe central neurological deficit. Discussion: We were unable to find a similar case in the literature, but we hypothesize that the temporal concidence of these clinical entities may be related to a common immunological pathway, such as B-cell activation. Therefore, we treated the patient with an immunosuppressant and anticoagulant treatment, as well as rituximab, a monoclonal antibody therapy against CD20+. Muscle Nerve 47:447-451, 2013

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Muscle and Nerve

ISSN

0148-639X

e-ISSN

—

Svazek periodika

47

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

447-451

Kód UT WoS článku

000315401500021

EID výsledku v databázi Scopus

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