Toxic Shock Syndrome and Persistent Immune Activation in an HIV-Positive Patient

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10191056" target="_blank" >RIV/00216208:11110/13:10191056 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064211:_____/13:#0000225

Výsledek na webu

<a href="http://dx.doi.org/10.2174/1570162X113119990045" target="_blank" >http://dx.doi.org/10.2174/1570162X113119990045</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2174/1570162X113119990045" target="_blank" >10.2174/1570162X113119990045</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Toxic Shock Syndrome and Persistent Immune Activation in an HIV-Positive Patient

Popis výsledku v původním jazyce

The case of an HIV-positive treatment-naive male with toxic shock syndrome (TSS) is presented herein. The course of TSS was favorable; however, the patient had extremely high plasma levels of MCP-1 and CD38 and HLA-DR expression on CD8+ T cells during the acute illness. Furthermore, the numbers of CD8+ T cells were reduced and CD4+ T cells remained stable during acute illness in comparison to baseline values. MCP-1 and HLA-DR gradually decreased, but they were still elevated after a month, whereas the number of circulating CD8+ T cells increased more than fivefold. CD38 expression remained stable during this period. A further decrease in CD38, HLA-DR and MCP-1 was noted five months after the initiation of antiretroviral therapy.

Název v anglickém jazyce

Toxic Shock Syndrome and Persistent Immune Activation in an HIV-Positive Patient

Popis výsledku anglicky

The case of an HIV-positive treatment-naive male with toxic shock syndrome (TSS) is presented herein. The course of TSS was favorable; however, the patient had extremely high plasma levels of MCP-1 and CD38 and HLA-DR expression on CD8+ T cells during the acute illness. Furthermore, the numbers of CD8+ T cells were reduced and CD4+ T cells remained stable during acute illness in comparison to baseline values. MCP-1 and HLA-DR gradually decreased, but they were still elevated after a month, whereas the number of circulating CD8+ T cells increased more than fivefold. CD38 expression remained stable during this period. A further decrease in CD38, HLA-DR and MCP-1 was noted five months after the initiation of antiretroviral therapy.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current HIV Research

ISSN

1570-162X

e-ISSN

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Svazek periodika

11

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

AE - Spojené arabské emiráty

Počet stran výsledku

5

Strana od-do

321-325

Kód UT WoS článku

000324868700009

EID výsledku v databázi Scopus

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