Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10193685" target="_blank" >RIV/00216208:11110/13:10193685 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14740/13:00072798 RIV/00064165:_____/13:10193685

Výsledek na webu

<a href="http://dx.doi.org/10.3109/00207454.2012.746335" target="_blank" >http://dx.doi.org/10.3109/00207454.2012.746335</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3109/00207454.2012.746335" target="_blank" >10.3109/00207454.2012.746335</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients

Popis výsledku v původním jazyce

There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examinea hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.

Název v anglickém jazyce

Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients

Popis výsledku anglicky

There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examinea hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Neuroscience

ISSN

0020-7454

e-ISSN

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Svazek periodika

123

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

204-208

Kód UT WoS článku

000314898000009

EID výsledku v databázi Scopus

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