Urinary Neopterin Concentration and Toxicity of Radiotherapy in Patients with Head and Neck Carcinoma During External Beam Radiation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10193692" target="_blank" >RIV/00216208:11110/13:10193692 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/13:10193692 RIV/00216208:11160/13:10193692 RIV/61989592:15110/13:33145190 RIV/00179906:_____/13:10193692 a 2 dalších

Výsledek na webu

<a href="http://ar.iiarjournals.org/content/33/9/4097.full" target="_blank" >http://ar.iiarjournals.org/content/33/9/4097.full</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Urinary Neopterin Concentration and Toxicity of Radiotherapy in Patients with Head and Neck Carcinoma During External Beam Radiation

Popis výsledku v původním jazyce

Aim: Increased serum or urinary concentrations of neopterin are predictive of poor prognosis in patients with tumors across a spectrum of primary locations. Less information is available about the significance of changes of urinary neopterin concentrations during therapy. The aim of the present study was to examine the association between urinary neopterin and toxicity of radiotherapy. Patients and Methods: We analyzed changes of urinary neopterin and toxicity of therapy in 12 patients with head and neck carcinoma during external-beam radiation. Urinary neopterin was determined daily by high-performance liquid chromatography. Results: In addition to a trend for increased neopterin concentrations during radiation therapy, a significant association between changes of neopterin and toxicity and vice versa was observed with a rise of neopterin predicting a later manifestation of toxicity as well as manifestion of toxicity predicting a later rise of neopterin. Conclusion: Urinary neopterin

Název v anglickém jazyce

Urinary Neopterin Concentration and Toxicity of Radiotherapy in Patients with Head and Neck Carcinoma During External Beam Radiation

Popis výsledku anglicky

Aim: Increased serum or urinary concentrations of neopterin are predictive of poor prognosis in patients with tumors across a spectrum of primary locations. Less information is available about the significance of changes of urinary neopterin concentrations during therapy. The aim of the present study was to examine the association between urinary neopterin and toxicity of radiotherapy. Patients and Methods: We analyzed changes of urinary neopterin and toxicity of therapy in 12 patients with head and neck carcinoma during external-beam radiation. Urinary neopterin was determined daily by high-performance liquid chromatography. Results: In addition to a trend for increased neopterin concentrations during radiation therapy, a significant association between changes of neopterin and toxicity and vice versa was observed with a rise of neopterin predicting a later manifestation of toxicity as well as manifestion of toxicity predicting a later rise of neopterin. Conclusion: Urinary neopterin

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

—

Projekt

<a href="/cs/project/ED0030%2F01%2F01" target="_blank" >ED0030/01/01: Biomedicína pro regionální rozvoj a lidské zdroje</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Anticancer Research

ISSN

0250-7005

e-ISSN

—

Svazek periodika

33

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

GR - Řecká republika

Počet stran výsledku

5

Strana od-do

4097-4101

Kód UT WoS článku

000327055200078

EID výsledku v databázi Scopus

—