SISCOM and FDG-PET in patients with non-lesional extratemporal epilepsy: correlation with intracranial EEG, histology, and seizure outcome

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10193764" target="_blank" >RIV/00216208:11110/13:10193764 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61383082:_____/13:0014 RIV/00216208:11130/13:10193764 RIV/00064203:_____/13:10193764

Výsledek na webu

<a href="http://dx.doi.org/10.1684/epd.2013.0560" target="_blank" >http://dx.doi.org/10.1684/epd.2013.0560</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1684/epd.2013.0560" target="_blank" >10.1684/epd.2013.0560</a>

Jazyk výsledku

angličtina

Název v původním jazyce

SISCOM and FDG-PET in patients with non-lesional extratemporal epilepsy: correlation with intracranial EEG, histology, and seizure outcome

Popis výsledku v původním jazyce

Aims. To assess the practical localising value of subtraction ictal single-photon emission computed tomography (SISCOM) coregistered with MRI and F-18-fluorodeoxyglucose positron emission tomography (FDG-PET) in patients with extratemporal epilepsy and normal MRI. Methods. We retrospectively studied a group of 14 patients who received surgery due to intractable epilepsy and who were shown to have focal cortical dysplasia, undetected by MRI, based on histological investigation. We coregistered preoperative SISCOM and PET images with postoperative MRI and visually determined whether the SISCOM focus, PET hypometabolic area, and cerebral cortex, exhibiting prominent abnormalities on intracranial EEG, were removed completely, incompletely, or not at all. These results and histopathological findings were compared with postoperative seizure outcome. Results. Two patients underwent one-stage multimodal image-guided surgery and the remaining 12 underwent long-term invasive EEG. SISCOM findings

Název v anglickém jazyce

SISCOM and FDG-PET in patients with non-lesional extratemporal epilepsy: correlation with intracranial EEG, histology, and seizure outcome

Popis výsledku anglicky

Aims. To assess the practical localising value of subtraction ictal single-photon emission computed tomography (SISCOM) coregistered with MRI and F-18-fluorodeoxyglucose positron emission tomography (FDG-PET) in patients with extratemporal epilepsy and normal MRI. Methods. We retrospectively studied a group of 14 patients who received surgery due to intractable epilepsy and who were shown to have focal cortical dysplasia, undetected by MRI, based on histological investigation. We coregistered preoperative SISCOM and PET images with postoperative MRI and visually determined whether the SISCOM focus, PET hypometabolic area, and cerebral cortex, exhibiting prominent abnormalities on intracranial EEG, were removed completely, incompletely, or not at all. These results and histopathological findings were compared with postoperative seizure outcome. Results. Two patients underwent one-stage multimodal image-guided surgery and the remaining 12 underwent long-term invasive EEG. SISCOM findings

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/ME09042" target="_blank" >ME09042: Zhodnocení významu iktálního SPECT v diagnostice kandidátů chirurgické léčby epilepsie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Epileptic Disorders

ISSN

1294-9361

e-ISSN

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Svazek periodika

15

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

11

Strana od-do

3-13

Kód UT WoS článku

000317594400002

EID výsledku v databázi Scopus

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