Nodal status is not a prognostic factor in patients with HPV-positive oral/oropharyngeal tumors
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10195283" target="_blank" >RIV/00216208:11110/13:10195283 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00064203:_____/13:10195283 RIV/00023736:_____/13:00010471
Výsledek na webu
<a href="http://dx.doi.org/10.1002/jso.23292" target="_blank" >http://dx.doi.org/10.1002/jso.23292</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jso.23292" target="_blank" >10.1002/jso.23292</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Nodal status is not a prognostic factor in patients with HPV-positive oral/oropharyngeal tumors
Popis výsledku v původním jazyce
Objectives The primary aim is to compare the prognostic parameters in patients with HPV-positive and HPV-negative tumors. The secondary aim is to compare the patterns of treatment failure between these groups. Methods Analysis of prognostic factors in agroup of 170 patients. Results High-risk HPV DNA was detected in 98 cases, 72 tumors were HPV negative. Both the overall and disease-specific survival rates were better in HPV-positive patients. In patients with HPV-negative tumors, the prognostic factors in univariate analysis were pT and pN classification, tumor stage, number of positive nodes, and extracapsular spread. Stage, pT, higher pN, and number of nodes maintained statistical significance after adjustment. None of the studied prognostic factors was significant in the group of patients with HPV-positive tumors. There was a significant difference in the localregional recurrence rates37% in HPV-negative cases and 18% in HPV-positive cases. Conclusion The characteristics of the ex
Název v anglickém jazyce
Nodal status is not a prognostic factor in patients with HPV-positive oral/oropharyngeal tumors
Popis výsledku anglicky
Objectives The primary aim is to compare the prognostic parameters in patients with HPV-positive and HPV-negative tumors. The secondary aim is to compare the patterns of treatment failure between these groups. Methods Analysis of prognostic factors in agroup of 170 patients. Results High-risk HPV DNA was detected in 98 cases, 72 tumors were HPV negative. Both the overall and disease-specific survival rates were better in HPV-positive patients. In patients with HPV-negative tumors, the prognostic factors in univariate analysis were pT and pN classification, tumor stage, number of positive nodes, and extracapsular spread. Stage, pT, higher pN, and number of nodes maintained statistical significance after adjustment. None of the studied prognostic factors was significant in the group of patients with HPV-positive tumors. There was a significant difference in the localregional recurrence rates37% in HPV-negative cases and 18% in HPV-positive cases. Conclusion The characteristics of the ex
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FF - ORL, oftalmologie, stomatologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NT12483" target="_blank" >NT12483: Vztah virové etiologie nádorů orofaryngu k úspěšnosti jednotlivých léčebných modalit</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2013
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Surgical Oncology
ISSN
0022-4790
e-ISSN
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Svazek periodika
107
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
9
Strana od-do
625-633
Kód UT WoS článku
000317939400013
EID výsledku v databázi Scopus
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