Combining ultrasound-guided fnac with elastography improves the sensitivity and specificity in pre-operative diagnostics of thyroid nodules and prediction of molecular markers expression?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10281147" target="_blank" >RIV/00216208:11110/14:10281147 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/14:10281147 RIV/00064165:_____/14:10281147

Výsledek na webu

<a href="http://www.americanij.com" target="_blank" >http://www.americanij.com</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Combining ultrasound-guided fnac with elastography improves the sensitivity and specificity in pre-operative diagnostics of thyroid nodules and prediction of molecular markers expression?

Popis výsledku v původním jazyce

Background. The occurrence of thyroid nodules is common and ultrasound (US) examination reveals them in up to 50-60% of unselected population. Aim.To assess the correlation between US-guided elastography and US-guided FNAC (USG-FNAC) with results of definitive histology and the presence of BRAF and KRAS genes mutations and the VEGF-A gene expression in thyroid nodule. Subjects and methods. The case-control study included 32 patients/nodules (20 malignant and 12 benign as the control) operated in 2013 due thyroid nodules at the Department of Otolaryngology - Head and Neck Surgery, Na Homolce Hospital, Prague. The correlation of the elastography score with USG-FNAC and the difinitive histology with the genetic examination could be analyzed in 20 nodules.

Název v anglickém jazyce

Combining ultrasound-guided fnac with elastography improves the sensitivity and specificity in pre-operative diagnostics of thyroid nodules and prediction of molecular markers expression?

Popis výsledku anglicky

Background. The occurrence of thyroid nodules is common and ultrasound (US) examination reveals them in up to 50-60% of unselected population. Aim.To assess the correlation between US-guided elastography and US-guided FNAC (USG-FNAC) with results of definitive histology and the presence of BRAF and KRAS genes mutations and the VEGF-A gene expression in thyroid nodule. Subjects and methods. The case-control study included 32 patients/nodules (20 malignant and 12 benign as the control) operated in 2013 due thyroid nodules at the Department of Otolaryngology - Head and Neck Surgery, Na Homolce Hospital, Prague. The correlation of the elastography score with USG-FNAC and the difinitive histology with the genetic examination could be analyzed in 20 nodules.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FF - ORL, oftalmologie, stomatologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

American International Journal of Contemporary Scientific Research

ISSN

2349-4425

e-ISSN

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Svazek periodika

1

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

49-54

Kód UT WoS článku

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EID výsledku v databázi Scopus

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