Newborn Boys and Girls Differ in the Lipid Composition of Vernix Caseosa
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10282009" target="_blank" >RIV/00216208:11110/14:10282009 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61388963:_____/14:00429854 RIV/00216208:11310/14:10282009 RIV/00064165:_____/14:10282009
Výsledek na webu
<a href="http://dx.doi.org/10.1371/journal.pone.0099173" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0099173</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0099173" target="_blank" >10.1371/journal.pone.0099173</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Newborn Boys and Girls Differ in the Lipid Composition of Vernix Caseosa
Popis výsledku v původním jazyce
Vernix caseosa protects the skin of a human fetus during the last trimester of pregnancy and of a newborn after the delivery. Besides its cellular and proteinaceous components, an important constituent and functional agent is a complex lipid fraction, implicated in a multitude of salubrious effects of vernix caseosa. Little is known about how the chemical composition of vernix caseosa lipids is affected by various biological characteristics of the baby, such as the gestational age, birth weight, and, last but not least, the gender of the newborn. This study reports on the chemical variability of lipids contained in the vernix caseosa of twenty newborn girls and boys and shows that the quantitative patterns of the lipids are sex-specific. The specificity of lipids was investigated at the level of fatty acids in the total lipid extracts and intact lipids of several neutral lipid classes. Hydrocarbons, wax esters, cholesteryl esters, diol diesters and triacylglycerols were isolated using
Název v anglickém jazyce
Newborn Boys and Girls Differ in the Lipid Composition of Vernix Caseosa
Popis výsledku anglicky
Vernix caseosa protects the skin of a human fetus during the last trimester of pregnancy and of a newborn after the delivery. Besides its cellular and proteinaceous components, an important constituent and functional agent is a complex lipid fraction, implicated in a multitude of salubrious effects of vernix caseosa. Little is known about how the chemical composition of vernix caseosa lipids is affected by various biological characteristics of the baby, such as the gestational age, birth weight, and, last but not least, the gender of the newborn. This study reports on the chemical variability of lipids contained in the vernix caseosa of twenty newborn girls and boys and shows that the quantitative patterns of the lipids are sex-specific. The specificity of lipids was investigated at the level of fatty acids in the total lipid extracts and intact lipids of several neutral lipid classes. Hydrocarbons, wax esters, cholesteryl esters, diol diesters and triacylglycerols were isolated using
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CB - Analytická chemie, separace
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GAP206%2F12%2F0750" target="_blank" >GAP206/12/0750: Lipidom novorozeneckého mázku: komplexní analýza a biologická variabilita</a><br>
Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
PLoS ONE
ISSN
1932-6203
e-ISSN
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Svazek periodika
9
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
8
Strana od-do
1-8
Kód UT WoS článku
000337165600051
EID výsledku v databázi Scopus
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