The Application of Autologous Serum Eye Drops in Severe Dry Eye Patients; Subjective and Objective Parameters Before and After Treatment
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10282465" target="_blank" >RIV/00216208:11110/14:10282465 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00064165:_____/14:10282465
Výsledek na webu
<a href="http://dx.doi.org/10.3109/02713683.2013.824987" target="_blank" >http://dx.doi.org/10.3109/02713683.2013.824987</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/02713683.2013.824987" target="_blank" >10.3109/02713683.2013.824987</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The Application of Autologous Serum Eye Drops in Severe Dry Eye Patients; Subjective and Objective Parameters Before and After Treatment
Popis výsledku v původním jazyce
Aim: To assess the impact of autologous serum (AS) eye drops on the ocular surface of patients with bilateral severe dry eye and to draw a comparison between the clinical and laboratory examinations and the degree of subjective symptoms before and afterserum treatment. Materials and methods: A three-month prospective study was conducted on 17 patients with severe dry eye. AS eye drops were applied a maximum of 12 times a day together with regular therapy. Dry eye status was evaluated by clinical examination (visual acuity, Schirmer test, tear film breakup time, vital staining, tear film debris and meniscus), conjunctival impression cytology (epithelial and goblet cell density, snake-like chromatin, HLA-DR-positive and apoptotic cells) and subjectivelyby the patients. Results: The application of AS eye drops led to a significant improvement in the Schirmer test (p<0.01) and tear film debris (p<0.05). The densities of goblet (p<0.0001) and epithelial cells (p<0.05) were significantly i
Název v anglickém jazyce
The Application of Autologous Serum Eye Drops in Severe Dry Eye Patients; Subjective and Objective Parameters Before and After Treatment
Popis výsledku anglicky
Aim: To assess the impact of autologous serum (AS) eye drops on the ocular surface of patients with bilateral severe dry eye and to draw a comparison between the clinical and laboratory examinations and the degree of subjective symptoms before and afterserum treatment. Materials and methods: A three-month prospective study was conducted on 17 patients with severe dry eye. AS eye drops were applied a maximum of 12 times a day together with regular therapy. Dry eye status was evaluated by clinical examination (visual acuity, Schirmer test, tear film breakup time, vital staining, tear film debris and meniscus), conjunctival impression cytology (epithelial and goblet cell density, snake-like chromatin, HLA-DR-positive and apoptotic cells) and subjectivelyby the patients. Results: The application of AS eye drops led to a significant improvement in the Schirmer test (p<0.01) and tear film debris (p<0.05). The densities of goblet (p<0.0001) and epithelial cells (p<0.05) were significantly i
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FF - ORL, oftalmologie, stomatologie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NT12376" target="_blank" >NT12376: Porovnání účinků autologního séra a séra z pupečníkové krve po aplikaci pacientům s defekty na povrchu oka</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Current Eye Research
ISSN
0271-3683
e-ISSN
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Svazek periodika
39
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
10
Strana od-do
21-30
Kód UT WoS článku
000328121800003
EID výsledku v databázi Scopus
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