IgA Nephropathy in Czech Patients - Are We Able Reliably Predict the Outcome?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10282807" target="_blank" >RIV/00216208:11110/14:10282807 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/14:10282807 RIV/00023001:_____/14:00059166 RIV/00064165:_____/14:10282807

Výsledek na webu

<a href="http://dx.doi.org/10.1159/000368467" target="_blank" >http://dx.doi.org/10.1159/000368467</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000368467" target="_blank" >10.1159/000368467</a>

Jazyk výsledku

angličtina

Název v původním jazyce

IgA Nephropathy in Czech Patients - Are We Able Reliably Predict the Outcome?

Popis výsledku v původním jazyce

Background/Aims: The aim of our study was to retrospectively analyse data of 520 Czech patients with IgA nephropathy (IgAN) and to specify the risk factors affecting renal survival of IgAN patients. Methods: Cox proportional hazards regression model wasused to evaluate the effects of different variables on renal survival during a median follow up of six years. McNemar's test was used to analyse the progression of renal function according to Bartosik's formula. Results: In our retrospective analysis of520 Czech IgAN patients Cox proportional hazards regression model with five variables [hypertension, sex, GFR, proteinuria, age] was used. Significant regression coefficient was found for GFR, hypertension and proteinuria. Using stepwise algorithm GFR (OR = 3.09), hypertension (OR = 2.09) and proteinuria (OR = 1.97) were found as the most important factors for renal survival in our group of IgAN patients. Among patients with CKD 3 we found significantly better renal survival in patients

Název v anglickém jazyce

IgA Nephropathy in Czech Patients - Are We Able Reliably Predict the Outcome?

Popis výsledku anglicky

Background/Aims: The aim of our study was to retrospectively analyse data of 520 Czech patients with IgA nephropathy (IgAN) and to specify the risk factors affecting renal survival of IgAN patients. Methods: Cox proportional hazards regression model wasused to evaluate the effects of different variables on renal survival during a median follow up of six years. McNemar's test was used to analyse the progression of renal function according to Bartosik's formula. Results: In our retrospective analysis of520 Czech IgAN patients Cox proportional hazards regression model with five variables [hypertension, sex, GFR, proteinuria, age] was used. Significant regression coefficient was found for GFR, hypertension and proteinuria. Using stepwise algorithm GFR (OR = 3.09), hypertension (OR = 2.09) and proteinuria (OR = 1.97) were found as the most important factors for renal survival in our group of IgAN patients. Among patients with CKD 3 we found significantly better renal survival in patients

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Kidney and Blood Pressure Research

ISSN

1420-4096

e-ISSN

—

Svazek periodika

39

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

8

Strana od-do

555-562

Kód UT WoS článku

000347728100006

EID výsledku v databázi Scopus

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