Comparing Bioinformatic Gene Expression Profiling Methods: Microarray and RNA-Seq

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284020" target="_blank" >RIV/00216208:11110/14:10284020 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/14:10284020

Výsledek na webu

<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152252/pdf/medscimonitbasicres-20-138.pdf" target="_blank" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152252/pdf/medscimonitbasicres-20-138.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.12659/MSMBR.892101" target="_blank" >10.12659/MSMBR.892101</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparing Bioinformatic Gene Expression Profiling Methods: Microarray and RNA-Seq

Popis výsledku v původním jazyce

Understanding the control of gene expression is critical for our understanding of the relationship between genotype and phenotype. The need for reliable assessment of transcript abundance in biological samples has driven scientists to develop novel technologies such as DNA microarray and RNA-Seq to meet this demand. This review focuses on comparing the two most useful methods for whole transcriptome gene expression profiling. Microarrays are reliable and more cost effective than RNA-Seq for gene expression profiling in model organisms. RNA-Seq will eventually be used more routinely than microarray, but right now the techniques can be complementary to each other. Microarrays will not become obsolete but might be relegated to only a few uses. RNA-Seq clearly has a bright future in bioinformatic data collection.

Název v anglickém jazyce

Comparing Bioinformatic Gene Expression Profiling Methods: Microarray and RNA-Seq

Popis výsledku anglicky

Understanding the control of gene expression is critical for our understanding of the relationship between genotype and phenotype. The need for reliable assessment of transcript abundance in biological samples has driven scientists to develop novel technologies such as DNA microarray and RNA-Seq to meet this demand. This review focuses on comparing the two most useful methods for whole transcriptome gene expression profiling. Microarrays are reliable and more cost effective than RNA-Seq for gene expression profiling in model organisms. RNA-Seq will eventually be used more routinely than microarray, but right now the techniques can be complementary to each other. Microarrays will not become obsolete but might be relegated to only a few uses. RNA-Seq clearly has a bright future in bioinformatic data collection.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Medical science monitor basic research [online]

ISSN

2325-4416

e-ISSN

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Svazek periodika

20

Číslo periodika v rámci svazku

Neuveden

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

3

Strana od-do

138-141

Kód UT WoS článku

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EID výsledku v databázi Scopus

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