Recognition of anaplastic foci within low-grade gliomas using MR spectroscopy
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285576" target="_blank" >RIV/00216208:11110/14:10285576 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11120/14:43908219 RIV/00023001:_____/14:00059026 RIV/61383082:_____/14:#0000252
Výsledek na webu
<a href="http://dx.doi.org/10.3109/02688697.2013.872229" target="_blank" >http://dx.doi.org/10.3109/02688697.2013.872229</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/02688697.2013.872229" target="_blank" >10.3109/02688697.2013.872229</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Recognition of anaplastic foci within low-grade gliomas using MR spectroscopy
Popis výsledku v původním jazyce
The recognition of anaplastic foci within low-grade gliomas is of extreme importance in patients under follow-up for Grade II gliomas. We present the algorithm of MR spectroscopy (MRS)-guided brain biopsy and its correlation with tumour histology. Methods. Twenty-seven patients harbouring suspected Grade II/III glioma were examined on our 3T MR. 2D PRESS-CSI metabolite images of Choline/Creatine, Creatine/N-acetylaspartate and Choline/N-acetylaspartate were calculated and exported to the DICOM format. According to these maps, a stereobiopsy was performed at the point of maximum Choline/Creatine ratio prior to tumour resection. In the case of enhancing tumour, a subsequent biopsy was performed from the point of enhancement. Comparisons were made betweenthe histology of the biopsied specimens and the resected tumours. Results. Eleven tumours were diagnosed as high-grade and sixteen as low-grade lesions. The correlation between main spectroscopic ratios (Cho/Cr and Cho/NAA) was strongly
Název v anglickém jazyce
Recognition of anaplastic foci within low-grade gliomas using MR spectroscopy
Popis výsledku anglicky
The recognition of anaplastic foci within low-grade gliomas is of extreme importance in patients under follow-up for Grade II gliomas. We present the algorithm of MR spectroscopy (MRS)-guided brain biopsy and its correlation with tumour histology. Methods. Twenty-seven patients harbouring suspected Grade II/III glioma were examined on our 3T MR. 2D PRESS-CSI metabolite images of Choline/Creatine, Creatine/N-acetylaspartate and Choline/N-acetylaspartate were calculated and exported to the DICOM format. According to these maps, a stereobiopsy was performed at the point of maximum Choline/Creatine ratio prior to tumour resection. In the case of enhancing tumour, a subsequent biopsy was performed from the point of enhancement. Comparisons were made betweenthe histology of the biopsied specimens and the resected tumours. Results. Eleven tumours were diagnosed as high-grade and sixteen as low-grade lesions. The correlation between main spectroscopic ratios (Cho/Cr and Cho/NAA) was strongly
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FH - Neurologie, neurochirurgie, neurovědy
OECD FORD obor
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Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
British Journal of Neurosurgery
ISSN
0268-8697
e-ISSN
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Svazek periodika
28
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
6
Strana od-do
631-636
Kód UT WoS článku
000341753500010
EID výsledku v databázi Scopus
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