Epidemiological data and cancer risk assessment: cessation LAG and lingering effect concepts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285639" target="_blank" >RIV/00216208:11110/14:10285639 - isvavai.cz</a>

Výsledek na webu

<a href="http://europepmc.org/abstract/med/25438399" target="_blank" >http://europepmc.org/abstract/med/25438399</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Epidemiological data and cancer risk assessment: cessation LAG and lingering effect concepts

Popis výsledku v původním jazyce

Cessation lag and lingering effect are two important aspects of risk assessment, and have potential applications to dose-response analysis in risk assessment. In addition to providing insight into biological mode of action, the concept of cessation lag is useful for economic benefit analysis. Concept of effect lingering can be used to analyze epidemiological data by uncovering the hidden biological implications related to disease endpoints, thereby advancing current efforts to characterize and reduce risk assessment uncertainties. Multicentre study design is proposed as a way to increase study size and to mitigate criticism of meta-analysis of independent studies. Individual studies from a multicentre study can be either pooled using original data, orcombined by meta-analysis of summarized results. A multicentre study of large cohort or case-control study also offers an exciting opportunity to study the contribution of epigenetic events that may be associated with life-style and envir

Název v anglickém jazyce

Epidemiological data and cancer risk assessment: cessation LAG and lingering effect concepts

Popis výsledku anglicky

Cessation lag and lingering effect are two important aspects of risk assessment, and have potential applications to dose-response analysis in risk assessment. In addition to providing insight into biological mode of action, the concept of cessation lag is useful for economic benefit analysis. Concept of effect lingering can be used to analyze epidemiological data by uncovering the hidden biological implications related to disease endpoints, thereby advancing current efforts to characterize and reduce risk assessment uncertainties. Multicentre study design is proposed as a way to increase study size and to mitigate criticism of meta-analysis of independent studies. Individual studies from a multicentre study can be either pooled using original data, orcombined by meta-analysis of summarized results. A multicentre study of large cohort or case-control study also offers an exciting opportunity to study the contribution of epigenetic events that may be associated with life-style and envir

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Central European Journal of Public Health

ISSN

1210-7778

e-ISSN

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Svazek periodika

22

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

197-200

Kód UT WoS článku

000343967200012

EID výsledku v databázi Scopus

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