Epidemiological data and cancer risk assessment: cessation LAG and lingering effect concepts
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285639" target="_blank" >RIV/00216208:11110/14:10285639 - isvavai.cz</a>
Výsledek na webu
<a href="http://europepmc.org/abstract/med/25438399" target="_blank" >http://europepmc.org/abstract/med/25438399</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Epidemiological data and cancer risk assessment: cessation LAG and lingering effect concepts
Popis výsledku v původním jazyce
Cessation lag and lingering effect are two important aspects of risk assessment, and have potential applications to dose-response analysis in risk assessment. In addition to providing insight into biological mode of action, the concept of cessation lag is useful for economic benefit analysis. Concept of effect lingering can be used to analyze epidemiological data by uncovering the hidden biological implications related to disease endpoints, thereby advancing current efforts to characterize and reduce risk assessment uncertainties. Multicentre study design is proposed as a way to increase study size and to mitigate criticism of meta-analysis of independent studies. Individual studies from a multicentre study can be either pooled using original data, orcombined by meta-analysis of summarized results. A multicentre study of large cohort or case-control study also offers an exciting opportunity to study the contribution of epigenetic events that may be associated with life-style and envir
Název v anglickém jazyce
Epidemiological data and cancer risk assessment: cessation LAG and lingering effect concepts
Popis výsledku anglicky
Cessation lag and lingering effect are two important aspects of risk assessment, and have potential applications to dose-response analysis in risk assessment. In addition to providing insight into biological mode of action, the concept of cessation lag is useful for economic benefit analysis. Concept of effect lingering can be used to analyze epidemiological data by uncovering the hidden biological implications related to disease endpoints, thereby advancing current efforts to characterize and reduce risk assessment uncertainties. Multicentre study design is proposed as a way to increase study size and to mitigate criticism of meta-analysis of independent studies. Individual studies from a multicentre study can be either pooled using original data, orcombined by meta-analysis of summarized results. A multicentre study of large cohort or case-control study also offers an exciting opportunity to study the contribution of epigenetic events that may be associated with life-style and envir
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FN - Epidemiologie, infekční nemoci a klinická imunologie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Central European Journal of Public Health
ISSN
1210-7778
e-ISSN
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Svazek periodika
22
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
4
Strana od-do
197-200
Kód UT WoS článku
000343967200012
EID výsledku v databázi Scopus
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