Heterochromatin variants in human karyotypes: a possible association with reproductive failure
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10287009" target="_blank" >RIV/00216208:11110/14:10287009 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00064165:_____/14:10287009
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.rbmo.2014.04.021" target="_blank" >http://dx.doi.org/10.1016/j.rbmo.2014.04.021</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.rbmo.2014.04.021" target="_blank" >10.1016/j.rbmo.2014.04.021</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Heterochromatin variants in human karyotypes: a possible association with reproductive failure
Popis výsledku v původním jazyce
Heterochromatin variants are commonly found during cytogenetic examinations, and chromosomes 1, 9, 16 and Y are commonly involved in these variations. These variants are believed to be clinically insignificant variations in human karyotypes. Nevertheless, reproductive failure has been frequently discussed as possibly being associated with these variants. Various authors have reported a significantly elevated incidence of these variants in individuals with idiopathic reproductive failure compared with individuals with no such history. This study compared the incidence of heterochromatin variants in individuals with idiopathic reproductive failure (n = 1036) with that of a control group of healthy fetuses (n = 995) indicated for prenatal karyotype examination solely based on the advanced ages of their mothers. The heterochromatin variants occurred more frequently in the reproductive failure group than in the controls (P = 0.006). Regarding individual chromosomes, chromosome 9 variants we
Název v anglickém jazyce
Heterochromatin variants in human karyotypes: a possible association with reproductive failure
Popis výsledku anglicky
Heterochromatin variants are commonly found during cytogenetic examinations, and chromosomes 1, 9, 16 and Y are commonly involved in these variations. These variants are believed to be clinically insignificant variations in human karyotypes. Nevertheless, reproductive failure has been frequently discussed as possibly being associated with these variants. Various authors have reported a significantly elevated incidence of these variants in individuals with idiopathic reproductive failure compared with individuals with no such history. This study compared the incidence of heterochromatin variants in individuals with idiopathic reproductive failure (n = 1036) with that of a control group of healthy fetuses (n = 995) indicated for prenatal karyotype examination solely based on the advanced ages of their mothers. The heterochromatin variants occurred more frequently in the reproductive failure group than in the controls (P = 0.006). Regarding individual chromosomes, chromosome 9 variants we
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FK - Gynekologie a porodnictví
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Reproductive BioMedicine Online
ISSN
1472-6483
e-ISSN
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Svazek periodika
29
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
6
Strana od-do
245-250
Kód UT WoS článku
000341378100014
EID výsledku v databázi Scopus
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