Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10292401" target="_blank" >RIV/00216208:11110/14:10292401 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/14:10292401

Výsledek na webu

<a href="http://dx.doi.org/10.1002/elps.201400046" target="_blank" >http://dx.doi.org/10.1002/elps.201400046</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elps.201400046" target="_blank" >10.1002/elps.201400046</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis

Popis výsledku v původním jazyce

DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator (R) Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134, DXS742. Haplotype frequencies were calculated for each LG (Linkage Group). The frequency of most common haplotype was 0.016, 0.036, 0.042, and 0.023 for LG1, LG2, LG3, and LG4, respectively. The combined power of discrimination was more than 0.999999999 both for female and male samples. The mean exclusion chance was 0.99999999 (trios) and 0.999999 (duos). Informativity and suitability of Investigator (R) Argus X-12 for kinship determination was assessed by computing in several female-female duos using LR (Likelihood Ratio) determination for autosomal STR (PowerPlex ESI-17), linked (Investigator (R) Argus X-12 system), and unlinked (X-STR Decaplex) X-STR kit

Název v anglickém jazyce

Investigator (R) Argus X-12 study on the population of Czech Republic: Comparison of linked and unlinked X-STRs for kinship analysis

Popis výsledku anglicky

DNA samples of 523 unrelated anonymized individuals (307 males and 216 females) born and living in the Czech Republic were genotyped using Investigator (R) Argus X-12 system in the following loci localized in four linkage groups: DXS10148, DXS10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134, DXS742. Haplotype frequencies were calculated for each LG (Linkage Group). The frequency of most common haplotype was 0.016, 0.036, 0.042, and 0.023 for LG1, LG2, LG3, and LG4, respectively. The combined power of discrimination was more than 0.999999999 both for female and male samples. The mean exclusion chance was 0.99999999 (trios) and 0.999999 (duos). Informativity and suitability of Investigator (R) Argus X-12 for kinship determination was assessed by computing in several female-female duos using LR (Likelihood Ratio) determination for autosomal STR (PowerPlex ESI-17), linked (Investigator (R) Argus X-12 system), and unlinked (X-STR Decaplex) X-STR kit

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electrophoresis

ISSN

0173-0835

e-ISSN

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Svazek periodika

35

Číslo periodika v rámci svazku

14

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

4

Strana od-do

1989-1992

Kód UT WoS článku

000339661300008

EID výsledku v databázi Scopus

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