Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson's Disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10294766" target="_blank" >RIV/00216208:11110/15:10294766 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216275:25410/15:39899783 RIV/00064165:_____/15:10294766

Výsledek na webu

<a href="http://dx.doi.org/10.1155/2015/709191" target="_blank" >http://dx.doi.org/10.1155/2015/709191</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2015/709191" target="_blank" >10.1155/2015/709191</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson's Disease

Popis výsledku v původním jazyce

Parkinson's disease (PD) is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH). The aim of our study was to establish whether patients with PD and visual hallucinations (PDH+) have structural changes of retina detected by an optical coherence tomography (OCT) in comparison with PD patients without visual hallucinations (PDH-). We examined 52 PD patients (18 with VH, 34 without VH) and 15 age and sex matched healthy controls. Retinal nerve fiber layer (RNFL) thickness and macular thickness and volume were assessed by OCT. Functional impairment of retina was assessed using 2.5% contrast sensitivity test. For OCT outcomes we analyzed 15 PDH+ and 15 PDH- subjects matched for age, gender, and PD duration. For contrast sensitivity we analyzed 8 pairs of patients matched for age, gender, and visual acuity. There was no significant difference in RNFL thickness and macular thickness and macular volume between 15 PDH+ and 15 PDH subjects,

Název v anglickém jazyce

Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson's Disease

Popis výsledku anglicky

Parkinson's disease (PD) is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH). The aim of our study was to establish whether patients with PD and visual hallucinations (PDH+) have structural changes of retina detected by an optical coherence tomography (OCT) in comparison with PD patients without visual hallucinations (PDH-). We examined 52 PD patients (18 with VH, 34 without VH) and 15 age and sex matched healthy controls. Retinal nerve fiber layer (RNFL) thickness and macular thickness and volume were assessed by OCT. Functional impairment of retina was assessed using 2.5% contrast sensitivity test. For OCT outcomes we analyzed 15 PDH+ and 15 PDH- subjects matched for age, gender, and PD duration. For contrast sensitivity we analyzed 8 pairs of patients matched for age, gender, and visual acuity. There was no significant difference in RNFL thickness and macular thickness and macular volume between 15 PDH+ and 15 PDH subjects,

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/NT13239" target="_blank" >NT13239: Fenotypizace axonálního postižení u RS na základě in vivo měření retinální patologie pomocí OCT</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Parkinson's Disease [online]

ISSN

2090-8083

e-ISSN

—

Svazek periodika

Neuveden

Číslo periodika v rámci svazku

February

Stát vydavatele periodika

EG - Egyptská arabská republika

Počet stran výsledku

6

Strana od-do

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Kód UT WoS článku

000349850500001

EID výsledku v databázi Scopus

2-s2.0-84924038107