Predicting Falls in Parkinson Disease: What Is the Value of Instrumented Testing in OFF Medication State?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10311844" target="_blank" >RIV/00216208:11110/15:10311844 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21230/15:00232660 RIV/00216208:11510/15:10311844 RIV/00064165:_____/15:10311844

Výsledek na webu

<a href="http://dx.doi.org/10.1371/journal.pone.0139849" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0139849</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.pone.0139849" target="_blank" >10.1371/journal.pone.0139849</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Predicting Falls in Parkinson Disease: What Is the Value of Instrumented Testing in OFF Medication State?

Popis výsledku v původním jazyce

Background Falls are a common complication of advancing Parkinson's disease (PD). Although numerous risk factors are known, reliable predictors of future falls are still lacking. The objective of this prospective study was to investigate clinical and instrumented tests of balance and gait in both OFF and ON medication states and to verify their utility in the prediction of future falls in PD patients. Methods Forty-five patients with idiopathic PD were examined in defined OFF and ON medication states within one examination day including PD-specific clinical tests, instrumented Timed Up and Go test (iTUG) and computerized dynamic posturography. The same gait and balance tests were performed in 22 control subjects of comparable age and sex. Participantswere then followed-up for 6 months using monthly fall diaries and phone calls. Results During the follow-up period, 27/45 PD patients and 4/22 control subjects fell one or more times. Previous falls, fear of falling, more severe motor imp

Název v anglickém jazyce

Predicting Falls in Parkinson Disease: What Is the Value of Instrumented Testing in OFF Medication State?

Popis výsledku anglicky

Background Falls are a common complication of advancing Parkinson's disease (PD). Although numerous risk factors are known, reliable predictors of future falls are still lacking. The objective of this prospective study was to investigate clinical and instrumented tests of balance and gait in both OFF and ON medication states and to verify their utility in the prediction of future falls in PD patients. Methods Forty-five patients with idiopathic PD were examined in defined OFF and ON medication states within one examination day including PD-specific clinical tests, instrumented Timed Up and Go test (iTUG) and computerized dynamic posturography. The same gait and balance tests were performed in 22 control subjects of comparable age and sex. Participantswere then followed-up for 6 months using monthly fall diaries and phone calls. Results During the follow-up period, 27/45 PD patients and 4/22 control subjects fell one or more times. Previous falls, fear of falling, more severe motor imp

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PLoS ONE

ISSN

1932-6203

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

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Kód UT WoS článku

000362510600091

EID výsledku v databázi Scopus

2-s2.0-84948683628