Mucosal Immunity in the Human Female Reproductive Tract

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10321865" target="_blank" >RIV/00216208:11110/15:10321865 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/B978-0-12-415847-4.00108-7" target="_blank" >http://dx.doi.org/10.1016/B978-0-12-415847-4.00108-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/B978-0-12-415847-4.00108-7" target="_blank" >10.1016/B978-0-12-415847-4.00108-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Mucosal Immunity in the Human Female Reproductive Tract

Popis výsledku v původním jazyce

The mucosal immune system in the human female reproductive tract is unique and distinct from all other mucosal surfaces. Consisting of the innate and adaptive immune systems, immune protection has evolved to meet the constraints of protecting against potential viral, bacterial and fungal pathogens while ensuring reproductive success of an allogeneic conceptus. In this review, we focus on our current understanding of role of sex hormones in regulating mucosal immunity throughout the female reproductive tract. Consisting of several compartments including the Fallopian tubes, uterus, endocervix, ectocervix, and vagina, each site is precisely and independently regulated by the ovarian production of estradiol and progesterone. These hormones act both directly and indirectly through cytokines, chemokines, and growth factors, to regulate immune cell phenotype and function as well as immune protection in reproductive tract secretions. Understanding the immune system in the female reproductive

Název v anglickém jazyce

Mucosal Immunity in the Human Female Reproductive Tract

Popis výsledku anglicky

The mucosal immune system in the human female reproductive tract is unique and distinct from all other mucosal surfaces. Consisting of the innate and adaptive immune systems, immune protection has evolved to meet the constraints of protecting against potential viral, bacterial and fungal pathogens while ensuring reproductive success of an allogeneic conceptus. In this review, we focus on our current understanding of role of sex hormones in regulating mucosal immunity throughout the female reproductive tract. Consisting of several compartments including the Fallopian tubes, uterus, endocervix, ectocervix, and vagina, each site is precisely and independently regulated by the ovarian production of estradiol and progesterone. These hormones act both directly and indirectly through cytokines, chemokines, and growth factors, to regulate immune cell phenotype and function as well as immune protection in reproductive tract secretions. Understanding the immune system in the female reproductive

Druh

C - Kapitola v odborné knize

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Mucosal Immunology

ISBN

978-0-12-415847-4

Počet stran výsledku

28

Strana od-do

2097-2124

Počet stran knihy

2423

Název nakladatele

Elsevier

Místo vydání

Amsterdam

Kód UT WoS kapitoly

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