Utility of cardiac CT for evaluating delayed contrast enhancement in dilated cardiomyopathy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10366221" target="_blank" >RIV/00216208:11110/17:10366221 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/17:10366221

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00059-016-4515-4" target="_blank" >http://dx.doi.org/10.1007/s00059-016-4515-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00059-016-4515-4" target="_blank" >10.1007/s00059-016-4515-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Utility of cardiac CT for evaluating delayed contrast enhancement in dilated cardiomyopathy

Popis výsledku v původním jazyce

The presence of myocardial fibrosis is associated with adverse outcome in dilated cardiomyopathy (DCM). Delayed contrast-enhanced cardiac magnetic resonance (DE-CMR) currently represents the gold standard in noninvasive evaluation of myocardial scarring. However, a significant number of patients are unable to undergo DE-CMR study for various reasons. We sought to determine the diagnostic accuracy of cardiac CT (CCT) compared with CMR in the investigation of the presence of delayed contrast enhancement (DCE) in subjects with DCM. We prospectively enrolled 17 consecutive patients with DCM, who were initially referred to our institution because of recently manifested heart failure due to unexplained left ventricular systolic dysfunction. In all subjects, CCT and DE-CMR were performed within 1 week. CCT and DE-CMR showed satisfactory agreement in detecting DCE (agreement in 82% cases, kappa = 0.56) with 50% sensitivity, 100% specificity, and a positive predictive value of 100%. CCT may be a valuable method for detecting DCE in patients with DCM. CCT thus might be considered as an alternative method to DE-CMR in the assessment of the presence and extent of myocardial fibrosis in subjects who are not suitable for DE-CMR examination.

Název v anglickém jazyce

Utility of cardiac CT for evaluating delayed contrast enhancement in dilated cardiomyopathy

Popis výsledku anglicky

The presence of myocardial fibrosis is associated with adverse outcome in dilated cardiomyopathy (DCM). Delayed contrast-enhanced cardiac magnetic resonance (DE-CMR) currently represents the gold standard in noninvasive evaluation of myocardial scarring. However, a significant number of patients are unable to undergo DE-CMR study for various reasons. We sought to determine the diagnostic accuracy of cardiac CT (CCT) compared with CMR in the investigation of the presence of delayed contrast enhancement (DCE) in subjects with DCM. We prospectively enrolled 17 consecutive patients with DCM, who were initially referred to our institution because of recently manifested heart failure due to unexplained left ventricular systolic dysfunction. In all subjects, CCT and DE-CMR were performed within 1 week. CCT and DE-CMR showed satisfactory agreement in detecting DCE (agreement in 82% cases, kappa = 0.56) with 50% sensitivity, 100% specificity, and a positive predictive value of 100%. CCT may be a valuable method for detecting DCE in patients with DCM. CCT thus might be considered as an alternative method to DE-CMR in the assessment of the presence and extent of myocardial fibrosis in subjects who are not suitable for DE-CMR examination.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Herz

ISSN

0340-9937

e-ISSN

—

Svazek periodika

42

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

776-780

Kód UT WoS článku

000417151500010

EID výsledku v databázi Scopus

2-s2.0-85006115556