Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10370928" target="_blank" >RIV/00216208:11110/18:10370928 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/27283933:_____/17:00004722 RIV/00216224:14110/18:00102945 RIV/00216208:11120/18:43913173 RIV/00064173:_____/18:N0000137 a 2 dalších

Výsledek na webu

<a href="https://doi.org/10.1016/j.crvasa.2017.02.007" target="_blank" >https://doi.org/10.1016/j.crvasa.2017.02.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crvasa.2017.02.007" target="_blank" >10.1016/j.crvasa.2017.02.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

Popis výsledku v původním jazyce

Background: The number of elderly patients in the population is rapidly increasing, and little is known about how adherence to recommended treatment strategies in elderly patients with acute coronary syndrome (ACS) has changed over time. Aim: To analyze trends in the treatment and outcomes of elderly patients with ACS from two registries conducted in the Czech Republic over 10 years. Methods and results: Data from the CZECH-1 and CZECH-3 registries were used in this study. These registries collected data in autumn 2005 and autumn 2015, and contain data from 1952 and 1754 unselected patients, respectively. All patients had been hospitalized with an initial diagnosis of ACS. There were 490 (25.7%) elderly patients in the CZECH-1 registry and 484 (28.1%) elderly patients in the CZECH-3 registry (p = 0.045) with an average age of 80.6 +- 4 and 82.1 +- 5 years (p &lt; 0.001), respectively. ACS was confirmed in 345 (72%) and 352 (73.6%) elderly patients (p = 0.781), respectively. There was higher use of percutaneous coronary intervention (65.2% and 54.8%; p &lt; 0.001), dual antiplatelet treatment, ACE inhibitors, and statins during treatment in the CZECH-3 compared to the CZECH-1 registry. No differences in hospital mortality of elderly patients with confirmed ACS were observed between registries (8.2% vs. 10.4%; p = 0.790). Conclusion: The proportion of patients with ACS that are elderly is increasing along with their increasing average age. Adherence to guideline-recommended therapy in this subgroup of patients has improved over time, but hospital mortality remains unchanged.

Název v anglickém jazyce

Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

Popis výsledku anglicky

Background: The number of elderly patients in the population is rapidly increasing, and little is known about how adherence to recommended treatment strategies in elderly patients with acute coronary syndrome (ACS) has changed over time. Aim: To analyze trends in the treatment and outcomes of elderly patients with ACS from two registries conducted in the Czech Republic over 10 years. Methods and results: Data from the CZECH-1 and CZECH-3 registries were used in this study. These registries collected data in autumn 2005 and autumn 2015, and contain data from 1952 and 1754 unselected patients, respectively. All patients had been hospitalized with an initial diagnosis of ACS. There were 490 (25.7%) elderly patients in the CZECH-1 registry and 484 (28.1%) elderly patients in the CZECH-3 registry (p = 0.045) with an average age of 80.6 +- 4 and 82.1 +- 5 years (p &lt; 0.001), respectively. ACS was confirmed in 345 (72%) and 352 (73.6%) elderly patients (p = 0.781), respectively. There was higher use of percutaneous coronary intervention (65.2% and 54.8%; p &lt; 0.001), dual antiplatelet treatment, ACE inhibitors, and statins during treatment in the CZECH-3 compared to the CZECH-1 registry. No differences in hospital mortality of elderly patients with confirmed ACS were observed between registries (8.2% vs. 10.4%; p = 0.790). Conclusion: The proportion of patients with ACS that are elderly is increasing along with their increasing average age. Adherence to guideline-recommended therapy in this subgroup of patients has improved over time, but hospital mortality remains unchanged.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cor et Vasa

ISSN

0010-8650

e-ISSN

—

Svazek periodika

60

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

"e66"-"e69"

Kód UT WoS článku

000426976600012

EID výsledku v databázi Scopus

2-s2.0-85017356129