Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23 weeks' gestation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10371144" target="_blank" >RIV/00216208:11110/18:10371144 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/18:43916168 RIV/00064165:_____/18:10371144

Výsledek na webu

<a href="http://dx.doi.org/10.1515/jpm-2016-0264" target="_blank" >http://dx.doi.org/10.1515/jpm-2016-0264</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/jpm-2016-0264" target="_blank" >10.1515/jpm-2016-0264</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23 weeks' gestation

Popis výsledku v původním jazyce

Objective: The aim of this single-center study was to identify factors that affect the short-term outcome of newborns delivered around the limits of viability. Methods: A group of 137 pregnant women who gave birth between 22+0/7 and 25+6/7 weeks of gestation was retrospectively studied. The center supports a proactive approach to infants around the limits of viability. Perinatal and neonatal characteristics were obtained and statistically evaluated. Results: A total of 166 live-born infants were enrolled during a 6-year period; 162 (97.6%) of them were admitted to the neonatal intensive care unit (ICU) and 119 (73.5%) survived until discharge. The decrease in neonatal mortality was associated with an advanced gestational age (P&lt;0.001) and a completed course of corticosteroids (P=0.002). Neonatal morbidities were common among infants of all gestational ages. The incidence of severe intraventricular hemorrhage significantly depended on gestational age (P&lt;0.001) and a completed course of corticosteroids (P=0.002). Survival without severe neonatal morbidities was 39.5% and occurred mostly after 24+0/7 weeks of gestation. Conclusion: The short-term outcome of newborns delivered around the limits of viability is mostly affected by gestational age and antenatal corticosteroid treatment. A consistently proactive approach improves the survival of infants at the limits of viability. This is most pronounced in cases where the delivery is delayed beyond 24 completed gestational weeks.

Název v anglickém jazyce

Proactive approach at the limits of viability improves the short-term outcome of neonates born after 23 weeks' gestation

Popis výsledku anglicky

Objective: The aim of this single-center study was to identify factors that affect the short-term outcome of newborns delivered around the limits of viability. Methods: A group of 137 pregnant women who gave birth between 22+0/7 and 25+6/7 weeks of gestation was retrospectively studied. The center supports a proactive approach to infants around the limits of viability. Perinatal and neonatal characteristics were obtained and statistically evaluated. Results: A total of 166 live-born infants were enrolled during a 6-year period; 162 (97.6%) of them were admitted to the neonatal intensive care unit (ICU) and 119 (73.5%) survived until discharge. The decrease in neonatal mortality was associated with an advanced gestational age (P&lt;0.001) and a completed course of corticosteroids (P=0.002). Neonatal morbidities were common among infants of all gestational ages. The incidence of severe intraventricular hemorrhage significantly depended on gestational age (P&lt;0.001) and a completed course of corticosteroids (P=0.002). Survival without severe neonatal morbidities was 39.5% and occurred mostly after 24+0/7 weeks of gestation. Conclusion: The short-term outcome of newborns delivered around the limits of viability is mostly affected by gestational age and antenatal corticosteroid treatment. A consistently proactive approach improves the survival of infants at the limits of viability. This is most pronounced in cases where the delivery is delayed beyond 24 completed gestational weeks.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Perinatal Medicine

ISSN

0300-5577

e-ISSN

—

Svazek periodika

46

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

9

Strana od-do

103-111

Kód UT WoS článku

000419583300014

EID výsledku v databázi Scopus

2-s2.0-85041479489