Maternal and obstetrical outcome in 35 cases of well-differentiated thyroid carcinoma during pregnancy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10375860" target="_blank" >RIV/00216208:11110/18:10375860 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/18:43915651 RIV/00064173:_____/18:N0000089 RIV/00064203:_____/18:10375860

Výsledek na webu

<a href="https://doi.org/10.1002/lary.26936" target="_blank" >https://doi.org/10.1002/lary.26936</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/lary.26936" target="_blank" >10.1002/lary.26936</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Maternal and obstetrical outcome in 35 cases of well-differentiated thyroid carcinoma during pregnancy

Popis výsledku v původním jazyce

Objectives/Hypothesis: Thyroid cancer, with 6% to 10% of cancer diagnoses, is one of the most common malignancies during pregnancy. Its treatment poses a risk for the pregnancy, as the thyroid gland plays a crucial role in the evolution of pregnancy. The aim of this study is to evaluate treatment of primary well-differentiated thyroid carcinoma during pregnancy and fetal and maternal outcomes. Study Design: This is an international cohort study. Methods: Primary thyroid cancer patients were identified from the database of the International Network on Cancer, Infertility, and Pregnancy registration study. Data on histopathological characteristics, diagnostic and therapeutic interventions, outcome (obstetrical, neonatal, and maternal) and maternal follow-up were analyzed. Results: Thirty-five patients with well-differentiated thyroid carcinoma were eligible. All 35 patients underwent surgery, 29 (83%) of which during pregnancy. Procedures during pregnancy were mainly total thyroidectomies (n = 24). The median number of days between diagnosis and surgical treatment was different between the groups with surgery during and after pregnancy (27 vs. 139 days, P &lt;.001). Both maternal and neonatal outcomes were uncomplicated, regardless of gestational age during surgery. Conclusions: Well-differentiated thyroid carcinoma diagnosed during pregnancy has a favorable outcome for both mother and child. Surgical management during pregnancy has no negative impact on the pregnancy regardless of the trimester at the time of surgery. However, the potential negative effects of thyroid surgery early in pregnancy demand management of these patients in an experienced multidisciplinary team to provide the best possible care for these patients and their unborn babies. Level of Evidence: 4. Laryngoscope, 128:1493-1500, 2018.

Název v anglickém jazyce

Maternal and obstetrical outcome in 35 cases of well-differentiated thyroid carcinoma during pregnancy

Popis výsledku anglicky

Objectives/Hypothesis: Thyroid cancer, with 6% to 10% of cancer diagnoses, is one of the most common malignancies during pregnancy. Its treatment poses a risk for the pregnancy, as the thyroid gland plays a crucial role in the evolution of pregnancy. The aim of this study is to evaluate treatment of primary well-differentiated thyroid carcinoma during pregnancy and fetal and maternal outcomes. Study Design: This is an international cohort study. Methods: Primary thyroid cancer patients were identified from the database of the International Network on Cancer, Infertility, and Pregnancy registration study. Data on histopathological characteristics, diagnostic and therapeutic interventions, outcome (obstetrical, neonatal, and maternal) and maternal follow-up were analyzed. Results: Thirty-five patients with well-differentiated thyroid carcinoma were eligible. All 35 patients underwent surgery, 29 (83%) of which during pregnancy. Procedures during pregnancy were mainly total thyroidectomies (n = 24). The median number of days between diagnosis and surgical treatment was different between the groups with surgery during and after pregnancy (27 vs. 139 days, P &lt;.001). Both maternal and neonatal outcomes were uncomplicated, regardless of gestational age during surgery. Conclusions: Well-differentiated thyroid carcinoma diagnosed during pregnancy has a favorable outcome for both mother and child. Surgical management during pregnancy has no negative impact on the pregnancy regardless of the trimester at the time of surgery. However, the potential negative effects of thyroid surgery early in pregnancy demand management of these patients in an experienced multidisciplinary team to provide the best possible care for these patients and their unborn babies. Level of Evidence: 4. Laryngoscope, 128:1493-1500, 2018.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

<a href="/cs/project/NV15-28933A" target="_blank" >NV15-28933A: Nádorové mikroprostředí karcinomů hlavy a krku: prognostický význam produkce mezibuněčné hmoty nádorově asociovanými fibroblasty</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The Laryngoscope

ISSN

0023-852X

e-ISSN

—

Svazek periodika

128

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

1493-1500

Kód UT WoS článku

000434179100046

EID výsledku v databázi Scopus

2-s2.0-85030652417