Relative position of the atrioventricular canal determines the electrical activation of developing reptile ventricles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10377525" target="_blank" >RIV/00216208:11110/18:10377525 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985823:_____/18:00493024

Výsledek na webu

<a href="https://doi.org/10.1242/jeb.178400" target="_blank" >https://doi.org/10.1242/jeb.178400</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1242/jeb.178400" target="_blank" >10.1242/jeb.178400</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Relative position of the atrioventricular canal determines the electrical activation of developing reptile ventricles

Popis výsledku v původním jazyce

Squamate reptiles appear to lack the specialized His-Purkinje system that enables the cardiac ventricle to be activated from apex to base as in mammals and birds. Instead, activation may simply spread from where the atrioventricular canal connects to the base. Gja5, which encodes Cx40, which allows fast impulse propagation, was expressed throughout the ventricles of developing anole lizards. Activation was optically recorded in developing corn snake and central bearded dragon. Early embryonic ventricles were broad in shape, and activation propagated from the base to the right. Elongated ventricles of later stages were activated from base to apex. Before hatching of the snake, the ventricle developed a cranial extension on the left and activation propagated from the base to the caudal apex and the cranial extension. In squamate reptiles, the pattern of electrical activation of the cardiac ventricle is dependent on the position of the atrioventricular canal and the shape of the ventricle.

Název v anglickém jazyce

Relative position of the atrioventricular canal determines the electrical activation of developing reptile ventricles

Popis výsledku anglicky

Squamate reptiles appear to lack the specialized His-Purkinje system that enables the cardiac ventricle to be activated from apex to base as in mammals and birds. Instead, activation may simply spread from where the atrioventricular canal connects to the base. Gja5, which encodes Cx40, which allows fast impulse propagation, was expressed throughout the ventricles of developing anole lizards. Activation was optically recorded in developing corn snake and central bearded dragon. Early embryonic ventricles were broad in shape, and activation propagated from the base to the right. Elongated ventricles of later stages were activated from base to apex. Before hatching of the snake, the ventricle developed a cranial extension on the left and activation propagated from the base to the caudal apex and the cranial extension. In squamate reptiles, the pattern of electrical activation of the cardiac ventricle is dependent on the position of the atrioventricular canal and the shape of the ventricle.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30106 - Anatomy and morphology (plant science to be 1.6)

Projekt

<a href="/cs/project/GA16-02972S" target="_blank" >GA16-02972S: Fylogenetický pohled na formování převodního systému srdečního</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Experimental Biology

ISSN

0022-0949

e-ISSN

—

Svazek periodika

221

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

—

Kód UT WoS článku

000438916100019

EID výsledku v databázi Scopus

2-s2.0-85048312946