Frequency of Complications During Preparation of Corneal Lamellae Used in Posterior Lamellar Keratoplasty Using the Pneumodissection Technique (Big Bubble)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10380158" target="_blank" >RIV/00216208:11110/18:10380158 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/18:43916670 RIV/00064173:_____/18:N0000002

Výsledek na webu

<a href="https://doi.org/10.1097/ICO.0000000000001503" target="_blank" >https://doi.org/10.1097/ICO.0000000000001503</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/ICO.0000000000001503" target="_blank" >10.1097/ICO.0000000000001503</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Frequency of Complications During Preparation of Corneal Lamellae Used in Posterior Lamellar Keratoplasty Using the Pneumodissection Technique (Big Bubble)

Popis výsledku v původním jazyce

Purpose: To determine the frequency of formation of various types of bubbles and the potential impact of donor and lamella parameters on this frequency, and to identify possible risk factors of unsuccessful &quot;big-bubble&quot; creation in preparation of pre-Descemet endothelial keratoplasty and Descemet membrane endothelial keratoplasty with peripheral stromal support. Methods: Donor age and sex, death to preservation time (DPT), storage time, presence of corneal scars (mainly a condition after cataract surgery), and endothelial cell density of 256 donor corneas were assessed before Descemet membrane endothelial keratoplasty with peripheral stromal support or pre-Descemet endothelial keratoplasty lamella preparation using the big-bubble technique. Results: Mean donor age was 62.3 +/- 8.5 years (28.3% women and 71.7% men). Mean endothelial cell density of the donor graft was 2866 +/- 255 cells/mm(2). Mean DPT was 10.12 +/- 4.88 hours, and mean storage time of the transplant before surgery was 6.5 +/- 4.8 days. Corneal scars were present in 17 donor grafts (6.6%) after cataract surgery. Eleven corneas were devalued because of Descemet membrane rupture during preparation (4.3%). In 182 corneas, standard bubble type I was created (71.7%); in 27 corneas, bubble type II was created; eventually, both types of bubbles formed simultaneously (10.5%); in 47 corneas, no bubble was created (18.4%). Conclusions: We identified higher endothelial cell density, shorter DPT, and the presence of corneal scars after cataract surgery as risk factors threatening successful bubble formation. The only risk factor for creating type II bubbles was higher donor age in our study.

Název v anglickém jazyce

Frequency of Complications During Preparation of Corneal Lamellae Used in Posterior Lamellar Keratoplasty Using the Pneumodissection Technique (Big Bubble)

Popis výsledku anglicky

Purpose: To determine the frequency of formation of various types of bubbles and the potential impact of donor and lamella parameters on this frequency, and to identify possible risk factors of unsuccessful &quot;big-bubble&quot; creation in preparation of pre-Descemet endothelial keratoplasty and Descemet membrane endothelial keratoplasty with peripheral stromal support. Methods: Donor age and sex, death to preservation time (DPT), storage time, presence of corneal scars (mainly a condition after cataract surgery), and endothelial cell density of 256 donor corneas were assessed before Descemet membrane endothelial keratoplasty with peripheral stromal support or pre-Descemet endothelial keratoplasty lamella preparation using the big-bubble technique. Results: Mean donor age was 62.3 +/- 8.5 years (28.3% women and 71.7% men). Mean endothelial cell density of the donor graft was 2866 +/- 255 cells/mm(2). Mean DPT was 10.12 +/- 4.88 hours, and mean storage time of the transplant before surgery was 6.5 +/- 4.8 days. Corneal scars were present in 17 donor grafts (6.6%) after cataract surgery. Eleven corneas were devalued because of Descemet membrane rupture during preparation (4.3%). In 182 corneas, standard bubble type I was created (71.7%); in 27 corneas, bubble type II was created; eventually, both types of bubbles formed simultaneously (10.5%); in 47 corneas, no bubble was created (18.4%). Conclusions: We identified higher endothelial cell density, shorter DPT, and the presence of corneal scars after cataract surgery as risk factors threatening successful bubble formation. The only risk factor for creating type II bubbles was higher donor age in our study.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

<a href="/cs/project/7F14156" target="_blank" >7F14156: Tissue engineering of genetically competent corneal and conjunctival cells for subsequent grafting in human medicine</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cornea

ISSN

0277-3740

e-ISSN

—

Svazek periodika

37

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

904-908

Kód UT WoS článku

000443070000028

EID výsledku v databázi Scopus

2-s2.0-85049401286