Problem Opioid Use in the Czech Republic from a Historical Perspective: Times are Changing but Opioid Pharmaceuticals Remain

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10406649" target="_blank" >RIV/00216208:11110/18:10406649 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ophIoFvtwb" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ophIoFvtwb</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Problem Opioid Use in the Czech Republic from a Historical Perspective: Times are Changing but Opioid Pharmaceuticals Remain

Popis výsledku v původním jazyce

SUMMARY: The prevalence of problem opioid use (POU) in the Czech Republic was estimated at 26.7% of 46,800 problem drug users in 2016, with buprenorphine being the most frequently used opioid. Although POU is not dominant in the Czech Republic because of the prevalent methamphetamine use, it still represents apublic health issue, also because of the high level of intravenous use. This article reviews the literature on the development of POU on the territory of the Czech Republic and describes several phases of this development: the use of opioid analgesics and domestic production before 1989, aheroin epidemic in the 1990s, and the decline in the use of heroin, which was replaced by diverted substitution medications (buprenorphine), and the recent return of the misuse of opioid analgesics as aconsequence of users looking for asubstance with an optimal cost/benefit ratio. Opioid analgesics are adesirable alternative to illicit opioids in various historical and socio-political contexts as they represent acheap and effective opioid drug. In conclusion, appropriate regulatory, preventive, and treatment measures, such as opioid maintenance treatment, are needed to alleviate the health and social harms associated with POU.

Název v anglickém jazyce

Problem Opioid Use in the Czech Republic from a Historical Perspective: Times are Changing but Opioid Pharmaceuticals Remain

Popis výsledku anglicky

SUMMARY: The prevalence of problem opioid use (POU) in the Czech Republic was estimated at 26.7% of 46,800 problem drug users in 2016, with buprenorphine being the most frequently used opioid. Although POU is not dominant in the Czech Republic because of the prevalent methamphetamine use, it still represents apublic health issue, also because of the high level of intravenous use. This article reviews the literature on the development of POU on the territory of the Czech Republic and describes several phases of this development: the use of opioid analgesics and domestic production before 1989, aheroin epidemic in the 1990s, and the decline in the use of heroin, which was replaced by diverted substitution medications (buprenorphine), and the recent return of the misuse of opioid analgesics as aconsequence of users looking for asubstance with an optimal cost/benefit ratio. Opioid analgesics are adesirable alternative to illicit opioids in various historical and socio-political contexts as they represent acheap and effective opioid drug. In conclusion, appropriate regulatory, preventive, and treatment measures, such as opioid maintenance treatment, are needed to alleviate the health and social harms associated with POU.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

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OECD FORD obor

30312 - Substance abuse

Projekt

<a href="/cs/project/NV16-28157A" target="_blank" >NV16-28157A: Kohorta žen užívajících metamfetamin, heroin a žen v opiátové substituci během těhotenství: neonatální a dlouhodobé následky pro dítě</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Adiktologie

ISSN

1213-3841

e-ISSN

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Svazek periodika

8

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

215-222

Kód UT WoS článku

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EID výsledku v databázi Scopus

2-s2.0-85083497805