Olfactory results of endoscopic endonasal surgery for pituitary adenoma: A prospective study of 143 patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F19%3A10394080" target="_blank" >RIV/00216208:11110/19:10394080 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/19:43918240 RIV/61383082:_____/19:00000491

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ufPMW7SJmK" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=ufPMW7SJmK</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.wneu.2019.05.061" target="_blank" >10.1016/j.wneu.2019.05.061</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Olfactory results of endoscopic endonasal surgery for pituitary adenoma: A prospective study of 143 patients

Popis výsledku v původním jazyce

BACKGROUND: Clinical examination, including pre- and postoperative assessment of olfaction function, should be included in evaluating surgical outcomes in patients with pituitary adenomas. Most of the studies are lacking assessment of olfactory function. METHODS: A prospective study with 143 patients who underwent surgical resection of pituitary adenomas from January 2014 to December 2017 was performed. Data on clinical presentation, pre- and postoperative neurologic, endocrinologic and ophthalmologic examinations, complications and follow-up outpatient examinations were recorded. Olfactory function was assessed using the Sniffin&apos; Sticks odor identification test preoperatively, postoperatively (3 months) and 1 year after surgery. RESULTS: Normosmia was present preoperatively in 93.7% of the patients, postoperatively in 95.8% and in 95.1% 1 year post-surgery. Hyposmia was present preoperatively in 4.2% of the patients, postoperatively in 2.1% and in 1.4% 1 year after surgery. Anosmia was present preoperatively in 2.1% of the patients, postoperatively in 2.1% and in 3.5% 1 year after surgery. In patients with preoperative normosmia postoperative hyposmia and anosmia were present in 1.5% of the patients. There were no differences according to age, gender, size or type of pituitary adenoma. CONCLUSIONS: Assessment of olfactory function should be included in the analysis of pituitary adenoma surgery results. This prospective study showed low risk of olfaction deterioration if an endoscopic endonasal approach is used without any mucosal flaps for skull base reconstruction. Further studies that include objective olfaction assessment are warranted.

Název v anglickém jazyce

Olfactory results of endoscopic endonasal surgery for pituitary adenoma: A prospective study of 143 patients

Popis výsledku anglicky

BACKGROUND: Clinical examination, including pre- and postoperative assessment of olfaction function, should be included in evaluating surgical outcomes in patients with pituitary adenomas. Most of the studies are lacking assessment of olfactory function. METHODS: A prospective study with 143 patients who underwent surgical resection of pituitary adenomas from January 2014 to December 2017 was performed. Data on clinical presentation, pre- and postoperative neurologic, endocrinologic and ophthalmologic examinations, complications and follow-up outpatient examinations were recorded. Olfactory function was assessed using the Sniffin&apos; Sticks odor identification test preoperatively, postoperatively (3 months) and 1 year after surgery. RESULTS: Normosmia was present preoperatively in 93.7% of the patients, postoperatively in 95.8% and in 95.1% 1 year post-surgery. Hyposmia was present preoperatively in 4.2% of the patients, postoperatively in 2.1% and in 1.4% 1 year after surgery. Anosmia was present preoperatively in 2.1% of the patients, postoperatively in 2.1% and in 3.5% 1 year after surgery. In patients with preoperative normosmia postoperative hyposmia and anosmia were present in 1.5% of the patients. There were no differences according to age, gender, size or type of pituitary adenoma. CONCLUSIONS: Assessment of olfactory function should be included in the analysis of pituitary adenoma surgery results. This prospective study showed low risk of olfaction deterioration if an endoscopic endonasal approach is used without any mucosal flaps for skull base reconstruction. Further studies that include objective olfaction assessment are warranted.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

World Neurosurgery

ISSN

1878-8750

e-ISSN

—

Svazek periodika

129

Číslo periodika v rámci svazku

September

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

"e907"-"e914"

Kód UT WoS článku

000481607900113

EID výsledku v databázi Scopus

2-s2.0-85067874366