Pre-exposure prophylaxis, a new approach for HIV prevention: experience from the HIV Center of the Military University Hospital Prague

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F20%3A10411708" target="_blank" >RIV/00216208:11110/20:10411708 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61383082:_____/20:00000968

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pa9s5MNRZj" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=pa9s5MNRZj</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Pre-exposure prophylaxis, a new approach for HIV prevention: experience from the HIV Center of the Military University Hospital Prague

Popis výsledku v původním jazyce

Aims: To present our experience with pre-exposure prophylaxis (PrEP) at the HIV Center of the Military University flospital Prague, to characterize a set of PrEP candidates, to assess the efficiency and safety of PrFP and to measure the incidence of sexually transmitted liseaks (STDs) in tlx studied cohort. Material and methods: In total, 99 PrEP candidates (98 men who have sex with men and one woman) were monitored during an 18 month period. An initial examination included acquiring a history, performing a physical examination, screening for HIV (serology) and other STDs and performing renal function tests. Results: In total. 81 candidates (in the cohort of 99 candidates) received PrEP. During the course of the 18-month period, none of the clients were newly infected with HIV, and no side effects of the provided medication were recorded. A total of 21% of the 99 PrEP candidates were initially tested positive for SIDs, including two clients with HIV. A total of 14% of the 81 PrEP clients contracted an STD during the monitoring period. Conclusions: Experience amassed at the HIV Center of the Military University Hospital Prague over an 18-month period documented the demand for PrEP, assessed PrEP efficacy, indicated good tolerance and suggested that PrEP played a role in the decline in the HIV incidence in the Czech Republic. In addition. several new HIV cases and cases of other asymptomatic STDs were also detected.

Název v anglickém jazyce

Pre-exposure prophylaxis, a new approach for HIV prevention: experience from the HIV Center of the Military University Hospital Prague

Popis výsledku anglicky

Aims: To present our experience with pre-exposure prophylaxis (PrEP) at the HIV Center of the Military University flospital Prague, to characterize a set of PrEP candidates, to assess the efficiency and safety of PrFP and to measure the incidence of sexually transmitted liseaks (STDs) in tlx studied cohort. Material and methods: In total, 99 PrEP candidates (98 men who have sex with men and one woman) were monitored during an 18 month period. An initial examination included acquiring a history, performing a physical examination, screening for HIV (serology) and other STDs and performing renal function tests. Results: In total. 81 candidates (in the cohort of 99 candidates) received PrEP. During the course of the 18-month period, none of the clients were newly infected with HIV, and no side effects of the provided medication were recorded. A total of 21% of the 99 PrEP candidates were initially tested positive for SIDs, including two clients with HIV. A total of 14% of the 81 PrEP clients contracted an STD during the monitoring period. Conclusions: Experience amassed at the HIV Center of the Military University Hospital Prague over an 18-month period documented the demand for PrEP, assessed PrEP efficacy, indicated good tolerance and suggested that PrEP played a role in the decline in the HIV incidence in the Czech Republic. In addition. several new HIV cases and cases of other asymptomatic STDs were also detected.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30303 - Infectious Diseases

Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Epidemiologie, mikrobiologie, imunologie

ISSN

1210-7913

e-ISSN

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Svazek periodika

69

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

38-41

Kód UT WoS článku

000531732800005

EID výsledku v databázi Scopus

2-s2.0-85084031368