Patient-reported symptoms are a more reliable predictor of the societal burden compared to established physician-reported activity indices in inflammatory bowel disease: a cross-sectional study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F23%3A10452641" target="_blank" >RIV/00216208:11110/23:10452641 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/23:00130126

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=qFit.dDBZ7" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=qFit.dDBZ7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/17474124.2023.2161047" target="_blank" >10.1080/17474124.2023.2161047</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Patient-reported symptoms are a more reliable predictor of the societal burden compared to established physician-reported activity indices in inflammatory bowel disease: a cross-sectional study

Popis výsledku v původním jazyce

Background: The societal burden of inflammatory bowel diseases (IBD) is not well documented, and further studies are needed to quantify the costs of the disease state. Thus, the aim was to estimate the societal burden and identify its predictors. Methods: A cross-sectional questionnaire-based study complemented by objective data from patient medical records was performed for patients with Crohn&apos;s disease (CD) and ulcerative colitis (UC). Results: We analyzed data from 161 patients (CD: 102, UC: 59). The overall work impairment reached 15.4%, 11.2% vs. 28.8% without/with self-reported symptoms (p = 0.006). Daily activity impairment was 19.3%, 14.1% vs. 35.6% (p &lt; 0.001). The disability pension rate was 28%, 23% vs. 44% (p = 0.012). The total productivity loss due to absenteeism, presenteeism, and disability amounted to 7,673 EUR/patient/year, 6,018 vs. 12,354 EUR/patient/year (p = 0.000). Out-of-pocket costs amounted to 562 EUR/patient/year, 472 vs. 844 EUR/patient/year (p = 0.001). Self-reported symptoms were the strongest predictor of costs (p &lt; 0.001). Conclusion: We found a high societal burden for IBD and a significant association between patient-reported disease symptoms and work disability, daily activity impairment, disability pensions, and out-of-pocket costs. Physician-reported disease activity is not a reliable predictor of costs except for out-of-pocket expenses.

Název v anglickém jazyce

Patient-reported symptoms are a more reliable predictor of the societal burden compared to established physician-reported activity indices in inflammatory bowel disease: a cross-sectional study

Popis výsledku anglicky

Background: The societal burden of inflammatory bowel diseases (IBD) is not well documented, and further studies are needed to quantify the costs of the disease state. Thus, the aim was to estimate the societal burden and identify its predictors. Methods: A cross-sectional questionnaire-based study complemented by objective data from patient medical records was performed for patients with Crohn&apos;s disease (CD) and ulcerative colitis (UC). Results: We analyzed data from 161 patients (CD: 102, UC: 59). The overall work impairment reached 15.4%, 11.2% vs. 28.8% without/with self-reported symptoms (p = 0.006). Daily activity impairment was 19.3%, 14.1% vs. 35.6% (p &lt; 0.001). The disability pension rate was 28%, 23% vs. 44% (p = 0.012). The total productivity loss due to absenteeism, presenteeism, and disability amounted to 7,673 EUR/patient/year, 6,018 vs. 12,354 EUR/patient/year (p = 0.000). Out-of-pocket costs amounted to 562 EUR/patient/year, 472 vs. 844 EUR/patient/year (p = 0.001). Self-reported symptoms were the strongest predictor of costs (p &lt; 0.001). Conclusion: We found a high societal burden for IBD and a significant association between patient-reported disease symptoms and work disability, daily activity impairment, disability pensions, and out-of-pocket costs. Physician-reported disease activity is not a reliable predictor of costs except for out-of-pocket expenses.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30219 - Gastroenterology and hepatology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Expert Review of Gastroenterology and Hepatology

ISSN

1747-4124

e-ISSN

1747-4132

Svazek periodika

17

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

99-108

Kód UT WoS článku

000901359300001

EID výsledku v databázi Scopus

2-s2.0-85145085556