Quantitative ultrasonographic assessment of the orbicularis oris muscle following cleft lip surgery: A case-control study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F25%3A10501900" target="_blank" >RIV/00216208:11110/25:10501900 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9MUlZ1bGef" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9MUlZ1bGef</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.aanat.2025.152715" target="_blank" >10.1016/j.aanat.2025.152715</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Quantitative ultrasonographic assessment of the orbicularis oris muscle following cleft lip surgery: A case-control study

Popis výsledku v původním jazyce

Background: This case-control study aimed to quantitatively assess the orbicularis oris muscle (OOM) in children with unilateral cleft lip and palate (UCLP) after primary lip repair using high-resolution ultrasonography, and to compare these measurements with children presenting isolated cleft palate (CP) without lip involvement. Methods: For this, 12 infants with UCLP who had undergone primary lip repair at 4-5 months of age were examined during subsequent palatoplasty at 9-12 months. They were compared to eight age-matched controls with isolated CP. Using a 22 MHz &quot;hockey stick&quot; transducer under general anaesthesia, muscle thickness (MT), height (MH), and cross-sectional area (CSA) of the OOM were measured on both sides of the upper lip. Results: The cleft side of the study group showed a significantly reduced CSA compared to the non-cleft side (p = 0.05), while MT was lower but not statistically significant. When compared with the control group, the cleft side showed significantly smaller CSA (p = 0.02) and MT (p = 0.05). No significant differences were observed between the non-cleft side and the control group, indicating normal muscle development on the unaffected side. Conclusions: Ultrasound proved to be a safe, reliable, and accessible tool for evaluating perioral muscle morphology in infants. The findings indicate persistent hypoplasia of the OOM on the cleft side post-repair, while the non-cleft side exhibits regular growth. These results may inform surgical technique selection and underline the potential of ultrasound for longitudinal studies. Future research could further enhance our understanding of muscle development and surgical outcomes in cleft patients.

Název v anglickém jazyce

Quantitative ultrasonographic assessment of the orbicularis oris muscle following cleft lip surgery: A case-control study

Popis výsledku anglicky

Background: This case-control study aimed to quantitatively assess the orbicularis oris muscle (OOM) in children with unilateral cleft lip and palate (UCLP) after primary lip repair using high-resolution ultrasonography, and to compare these measurements with children presenting isolated cleft palate (CP) without lip involvement. Methods: For this, 12 infants with UCLP who had undergone primary lip repair at 4-5 months of age were examined during subsequent palatoplasty at 9-12 months. They were compared to eight age-matched controls with isolated CP. Using a 22 MHz &quot;hockey stick&quot; transducer under general anaesthesia, muscle thickness (MT), height (MH), and cross-sectional area (CSA) of the OOM were measured on both sides of the upper lip. Results: The cleft side of the study group showed a significantly reduced CSA compared to the non-cleft side (p = 0.05), while MT was lower but not statistically significant. When compared with the control group, the cleft side showed significantly smaller CSA (p = 0.02) and MT (p = 0.05). No significant differences were observed between the non-cleft side and the control group, indicating normal muscle development on the unaffected side. Conclusions: Ultrasound proved to be a safe, reliable, and accessible tool for evaluating perioral muscle morphology in infants. The findings indicate persistent hypoplasia of the OOM on the cleft side post-repair, while the non-cleft side exhibits regular growth. These results may inform surgical technique selection and underline the potential of ultrasound for longitudinal studies. Future research could further enhance our understanding of muscle development and surgical outcomes in cleft patients.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30106 - Anatomy and morphology (plant science to be 1.6)

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Annals of Anatomy

ISSN

0940-9602

e-ISSN

1618-0402

Svazek periodika

262

Číslo periodika v rámci svazku

October

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

6

Strana od-do

152715

Kód UT WoS článku

001562667600001

EID výsledku v databázi Scopus

2-s2.0-105014279698