Interhemispheric and regional Metabolic Alterations in Posttraumatic Brains: An 18FDG PET Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F02%3A00003686" target="_blank" >RIV/00216208:11120/02:00003686 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Interhemispheric and regional Metabolic Alterations in Posttraumatic Brains: An 18FDG PET Study

Popis výsledku v původním jazyce

In a series of 10 patients with severe traumatic brain injury FDG PET studies were carried out in an interval of 1-62 months post trauma. They revealed decreased values of glucose metabolic turnover not only in the regions visibly affected on CT and MRI,but also in distant areas of the ipsi- and contralateral hemispheres. While the global metabolism of the injured hemispheres was decreased to 73% of healthy probands, also the,,unaffected" hemispheres in patients with unilateral lesions were suppressedto 80% of control values. Focal reductions of metabolism in traumatic regions were apparent in 9 cases, reaching a level of less than 20 mumol/100g tissue/min in 7 of them. In selected homolateral regions of interest beyond the apparent traumatic lesiona decreased metabolism lower than 80% of the contralateral analogous region was found in 6 patients, predominantly in the thalamus and putamen. Surprisingly also selected regions of increased metabolism in the injured hemisphere, compared

Název v anglickém jazyce

Interhemispheric and regional Metabolic Alterations in Posttraumatic Brains: An 18FDG PET Study

Popis výsledku anglicky

In a series of 10 patients with severe traumatic brain injury FDG PET studies were carried out in an interval of 1-62 months post trauma. They revealed decreased values of glucose metabolic turnover not only in the regions visibly affected on CT and MRI,but also in distant areas of the ipsi- and contralateral hemispheres. While the global metabolism of the injured hemispheres was decreased to 73% of healthy probands, also the,,unaffected" hemispheres in patients with unilateral lesions were suppressedto 80% of control values. Focal reductions of metabolism in traumatic regions were apparent in 9 cases, reaching a level of less than 20 mumol/100g tissue/min in 7 of them. In selected homolateral regions of interest beyond the apparent traumatic lesiona decreased metabolism lower than 80% of the contralateral analogous region was found in 6 patients, predominantly in the thalamus and putamen. Surprisingly also selected regions of increased metabolism in the injured hemisphere, compared

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2002

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a slovenská neurologie a neurochirurgie

ISSN

1210-7859

e-ISSN

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Svazek periodika

65

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

321-327

Kód UT WoS článku

000178949300003

EID výsledku v databázi Scopus

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