Cardiac troponin I release after transcatheter atrial septal defect closure depends on occluder size but not on patient's age

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F05%3A00002346" target="_blank" >RIV/00216208:11120/05:00002346 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Cardiac troponin I release after transcatheter atrial septal defect closure depends on occluder size but not on patient's age

Popis výsledku v původním jazyce

Objective: To examine whether transcatheter closure of secundum atrial septal defect (ASD) with the Amplatzer septal occluder leads to more myocardial injury in children than in adults. In a prospective study with children and adults cardiac troponin I (cTnI) serum concentrations were determined by immunoassay (AxSYM, Abbott Laboratories) before, during, and up to 20 months after surgical or transcatheter ASD closure. Patients: Four groups of patients were studied: transcatheter ASD closure ( group 1: 22 children, age range 3.26 - 14.7 years; group 2: 22 adults, 18.0 - 67.3 years), surgical ASD closure ( group 3: 18 children, 3.12 - 13.5 years), and diagnostic catheterisation ( group 4: 12 children, 2.68 - 15.0 years). Results: cTnI concentrations weresignificantly increased after occluder implantation with higher serum concentrations in children than in adults ( immediately after implantation: group 1, 3.2 (4.4) mug/l; group 2, 1.1 (4.2) mug/l; four hours after implantation: group 1,

Název v anglickém jazyce

Cardiac troponin I release after transcatheter atrial septal defect closure depends on occluder size but not on patient's age

Popis výsledku anglicky

Objective: To examine whether transcatheter closure of secundum atrial septal defect (ASD) with the Amplatzer septal occluder leads to more myocardial injury in children than in adults. In a prospective study with children and adults cardiac troponin I (cTnI) serum concentrations were determined by immunoassay (AxSYM, Abbott Laboratories) before, during, and up to 20 months after surgical or transcatheter ASD closure. Patients: Four groups of patients were studied: transcatheter ASD closure ( group 1: 22 children, age range 3.26 - 14.7 years; group 2: 22 adults, 18.0 - 67.3 years), surgical ASD closure ( group 3: 18 children, 3.12 - 13.5 years), and diagnostic catheterisation ( group 4: 12 children, 2.68 - 15.0 years). Results: cTnI concentrations weresignificantly increased after occluder implantation with higher serum concentrations in children than in adults ( immediately after implantation: group 1, 3.2 (4.4) mug/l; group 2, 1.1 (4.2) mug/l; four hours after implantation: group 1,

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Heart

ISSN

1355-6037

e-ISSN

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Svazek periodika

91

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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