Změny EEG tomografie (LORETA) u pacientů s farmakorezistentní depresí po 1 a 4 týdnech léčby v závislosti na klinické odpovědi

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F06%3A00000008" target="_blank" >RIV/00216208:11120/06:00000008 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023752:_____/06:00000598

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The response-specific changes in EEG tomography (LORETA) after 1 and 4 weeks of treatment in patients with drug-resistant depression

Popis výsledku v původním jazyce

Introduction: Previous studies of patients with unipolar depression have shown that depressive symptoms are caused by dysfunction of the limbic and frontal lobe regions and clinical response to treatment is associated with a reciprocal pattern of subcortical and limbic metabolic decreases and cortical increases. The aim of our study was to examine time-specific (1-week vs. baseline and 4-week vs. baseline) and response-specific (responders vs. non-responders) differences in brain electrical activities in patients with resistant depressive disorder. Method: The subjects were 25 inpatients with treatment resistant depression. EEG data and response to treatment were monitored at baseline and after 1 and 4 weeks on an antidepressant treatment. Low-resolution brain electromagnetic tomography (LORETA) was computed from spectrally analyzed EEG data, and differences between 1-week and 4-week treatment-induced changes in responders and non-responders were displayed as statistical parametric map

Název v anglickém jazyce

The response-specific changes in EEG tomography (LORETA) after 1 and 4 weeks of treatment in patients with drug-resistant depression

Popis výsledku anglicky

Introduction: Previous studies of patients with unipolar depression have shown that depressive symptoms are caused by dysfunction of the limbic and frontal lobe regions and clinical response to treatment is associated with a reciprocal pattern of subcortical and limbic metabolic decreases and cortical increases. The aim of our study was to examine time-specific (1-week vs. baseline and 4-week vs. baseline) and response-specific (responders vs. non-responders) differences in brain electrical activities in patients with resistant depressive disorder. Method: The subjects were 25 inpatients with treatment resistant depression. EEG data and response to treatment were monitored at baseline and after 1 and 4 weeks on an antidepressant treatment. Low-resolution brain electromagnetic tomography (LORETA) was computed from spectrally analyzed EEG data, and differences between 1-week and 4-week treatment-induced changes in responders and non-responders were displayed as statistical parametric map

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/1M0517" target="_blank" >1M0517: Centrum neuropsychiatrických studií 2005-2009 (Neurobiologie v klinické aplikaci)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Psychiatrie

ISSN

1211-7579

e-ISSN

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Svazek periodika

10

Číslo periodika v rámci svazku

Suppl. 3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

71-79

Kód UT WoS článku

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EID výsledku v databázi Scopus

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