Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F06%3A00000019" target="_blank" >RIV/00216208:11120/06:00000019 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023752:_____/06:00000597

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates

Popis výsledku v původním jazyce

Intracellular parasite Toxoplasma gondii (TG) is considered to be an infectious agent, which plays a role in the aetiology and pathogenesis of some cases of shizophrenia. TG infection-related cognitive dysfunction is considered as an element of vulnerability for the development of some schizophrenia subtypes. The hypothesis that links TG infection and schizophrenia is supported above all by these findings: a) a statistically significant increase of antibody titres to TG in first-episode schizophrenia patients, b) a positive correlation of the antibodies to TG and psychopathology scores in first-episode schizophrenia, c) an increased level of cognitive abnormalities in schizophrenia patients with serologic evidence of TG infection compared to the patients without signs of TG infection, and d) cognitive and personality changes in TG infected non-##schizophrenic subjects and behavioural changes in animal models. The objectives of the CNS project are to investigate TG infected and non-infe

Název v anglickém jazyce

Postnatal latent toxoplasmosis in schizophrenia: cognitive and psychopathological correlates

Popis výsledku anglicky

Intracellular parasite Toxoplasma gondii (TG) is considered to be an infectious agent, which plays a role in the aetiology and pathogenesis of some cases of shizophrenia. TG infection-related cognitive dysfunction is considered as an element of vulnerability for the development of some schizophrenia subtypes. The hypothesis that links TG infection and schizophrenia is supported above all by these findings: a) a statistically significant increase of antibody titres to TG in first-episode schizophrenia patients, b) a positive correlation of the antibodies to TG and psychopathology scores in first-episode schizophrenia, c) an increased level of cognitive abnormalities in schizophrenia patients with serologic evidence of TG infection compared to the patients without signs of TG infection, and d) cognitive and personality changes in TG infected non-##schizophrenic subjects and behavioural changes in animal models. The objectives of the CNS project are to investigate TG infected and non-infe

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

<a href="/cs/project/1M0517" target="_blank" >1M0517: Centrum neuropsychiatrických studií 2005-2009 (Neurobiologie v klinické aplikaci)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Psychiatrie

ISSN

1211-7579

e-ISSN

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Svazek periodika

10

Číslo periodika v rámci svazku

Suppl. 3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

66-70

Kód UT WoS článku

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EID výsledku v databázi Scopus

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