Korelace mezi funkční jaterní hmotou stanovenou pomocí dechového testu s 13C?methacetinem, ejekční frakcí levé komory a průměrem levé síně u nemocných s chronickým srdečním selháním

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F08%3A00000827" target="_blank" >RIV/00216208:11120/08:00000827 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Correlation of the functional liver mass with left ventricular ejection fraction and left atrial diameter in patients with congestive heart failure

Popis výsledku v původním jazyce

Background: Abnormalities in liver function tests have impact on prognosis of patients with chronic heart failure (CHF). The aim of the present study was to assess the functional liver mass in patient with systolic CHF with C-13-methacetin breath test. Patients and methods: Liver function was assessed with C-13-methacetin breath test in twenty patients, 15 men and 5 women, with systolic CHF, LVEF <= 45%, NYHA II-IV, and ten age and sex matched controls. The cumulative dose of exhaled (CO2)-C-13 was measured with an infrared analyzer. On the day of the breath test, routine liver function tests were determined and the echocardiographic studies were realized. Results: Functional liver mass was significantly decreased in patients at NYHA IV, compared to subjects with NYHA II, III and controls. Study revealed weak correlation of cumulative dose of 13CO2 with LV EF (r=0.47) and significant inverse correlation with left atrial diameter (r=-0.80, p < 0.0001) among other variables. Conclusions:

Název v anglickém jazyce

Correlation of the functional liver mass with left ventricular ejection fraction and left atrial diameter in patients with congestive heart failure

Popis výsledku anglicky

Background: Abnormalities in liver function tests have impact on prognosis of patients with chronic heart failure (CHF). The aim of the present study was to assess the functional liver mass in patient with systolic CHF with C-13-methacetin breath test. Patients and methods: Liver function was assessed with C-13-methacetin breath test in twenty patients, 15 men and 5 women, with systolic CHF, LVEF <= 45%, NYHA II-IV, and ten age and sex matched controls. The cumulative dose of exhaled (CO2)-C-13 was measured with an infrared analyzer. On the day of the breath test, routine liver function tests were determined and the echocardiographic studies were realized. Results: Functional liver mass was significantly decreased in patients at NYHA IV, compared to subjects with NYHA II, III and controls. Study revealed weak correlation of cumulative dose of 13CO2 with LV EF (r=0.47) and significant inverse correlation with left atrial diameter (r=-0.80, p < 0.0001) among other variables. Conclusions:

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Cardiology

ISSN

0167-5273

e-ISSN

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Svazek periodika

127

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

3

Strana od-do

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Kód UT WoS článku

000256661000024

EID výsledku v databázi Scopus

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