EEG source analysis in obsessive-compulsive disorder

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003163" target="_blank" >RIV/00216208:11120/11:00003163 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023752:_____/11:00001144 RIV/61989592:15110/11:33117316

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.clinph.2011.01.051" target="_blank" >http://dx.doi.org/10.1016/j.clinph.2011.01.051</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.clinph.2011.01.051" target="_blank" >10.1016/j.clinph.2011.01.051</a>

Jazyk výsledku

angličtina

Název v původním jazyce

EEG source analysis in obsessive-compulsive disorder

Popis výsledku v původním jazyce

The goal of this study was to assess the activity of intracortical EEG sources in patients with OCD. We compared resting state EEG from 50 OCD patients and 50 matched controls using standardized low-resolution electromagnetic tomography (sLORETA) and normative independent component analysis (NICA). Data were analyzed with 1 Hz frequency resolution. Group ICA was used to separate seven independent components from the control group data. The resulting weights and norms served to derive the same componentsfrom the OCD group and to compare their power with controls. In OCD, sLORETA indicated low-frequency power excess (2-6 Hz) in the medial frontal cortex, whereas group ICA showed increased low-frequency power in a component reflecting the activity of subgenual anterior cingulate, adjacent limbic structures and to a lesser extent also of lateral frontal cortex. Both methods provided evidence for medial frontal hyperactivation in OCD. Significance: Our study is the first to use normative I

Název v anglickém jazyce

EEG source analysis in obsessive-compulsive disorder

Popis výsledku anglicky

The goal of this study was to assess the activity of intracortical EEG sources in patients with OCD. We compared resting state EEG from 50 OCD patients and 50 matched controls using standardized low-resolution electromagnetic tomography (sLORETA) and normative independent component analysis (NICA). Data were analyzed with 1 Hz frequency resolution. Group ICA was used to separate seven independent components from the control group data. The resulting weights and norms served to derive the same componentsfrom the OCD group and to compare their power with controls. In OCD, sLORETA indicated low-frequency power excess (2-6 Hz) in the medial frontal cortex, whereas group ICA showed increased low-frequency power in a component reflecting the activity of subgenual anterior cingulate, adjacent limbic structures and to a lesser extent also of lateral frontal cortex. Both methods provided evidence for medial frontal hyperactivation in OCD. Significance: Our study is the first to use normative I

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

<a href="/cs/project/NS9751" target="_blank" >NS9751: Vliv EEG biofeedbacku na příznaky pacientů s obsedantně-kompulzivní poruchou, kteří neodpovídají na léčbu SSRIs</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Neurophysiology

ISSN

1388-2457

e-ISSN

—

Svazek periodika

122

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

9

Strana od-do

1735-1743

Kód UT WoS článku

000293267800008

EID výsledku v databázi Scopus

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