Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003192" target="_blank" >RIV/00216208:11120/11:00003192 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/11:10105879 RIV/00179906:_____/11:10105879

Výsledek na webu

<a href="http://www.signavitae.com/articles/original-articles/178-targeting-out-of-hospital-cardiac-arrest-the-effect-of-heparin-administered-during-cardiopulmonary-resuscitation-t-arrest" target="_blank" >http://www.signavitae.com/articles/original-articles/178-targeting-out-of-hospital-cardiac-arrest-the-effect-of-heparin-administered-during-cardiopulmonary-resuscitation-t-arrest</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST)

Popis výsledku v původním jazyce

Heparin administration during cardiopulmonary resuscitation (CPR) may prevent activation of coagulation after successful resuscitation for out-of-hospital cardiac arrest (OHCA). We hypothesize that such an approach is not associated with an increased rate of bleeding, but it has not been evaluated. We performed a pilot randomized clinical study assessing the safety of intra-arrest heparin administration in OHCA patients with suspected acute myocardial infarction (AMI) and its impact on their prognosis.OHCA patients were randomized during CPR to 10 000 units of intra-arrest intravenous heparin (Group H) or to treatment without heparin (Group C). The occurrence of major bleeding and the presence of a favourable neurological result 3 months after OHCA, were analyzed. Out of 88 randomized patients, AMI was subsequently confirmed in 63 of them (71.6 %). There were 30 patients in group H and 33 in group C. No major bleeding event was observed in either group. Return of spontaneous circulati

Název v anglickém jazyce

Targeting out-of-hospital cardiac arrest: The effect of heparin administered during cardiopulmonary resuscitation (T-ARREST)

Popis výsledku anglicky

Heparin administration during cardiopulmonary resuscitation (CPR) may prevent activation of coagulation after successful resuscitation for out-of-hospital cardiac arrest (OHCA). We hypothesize that such an approach is not associated with an increased rate of bleeding, but it has not been evaluated. We performed a pilot randomized clinical study assessing the safety of intra-arrest heparin administration in OHCA patients with suspected acute myocardial infarction (AMI) and its impact on their prognosis.OHCA patients were randomized during CPR to 10 000 units of intra-arrest intravenous heparin (Group H) or to treatment without heparin (Group C). The occurrence of major bleeding and the presence of a favourable neurological result 3 months after OHCA, were analyzed. Out of 88 randomized patients, AMI was subsequently confirmed in 63 of them (71.6 %). There were 30 patients in group H and 33 in group C. No major bleeding event was observed in either group. Return of spontaneous circulati

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

—

Projekt

<a href="/cs/project/NS10383" target="_blank" >NS10383: Nové terapeutické postupy základní a rozšířené neodkladné resuscitace na zvířecím modelu fibrilace komor</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Signa Vitae

ISSN

1334-5605

e-ISSN

—

Svazek periodika

6

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

HR - Chorvatská republika

Počet stran výsledku

7

Strana od-do

24-30

Kód UT WoS článku

000298179500003

EID výsledku v databázi Scopus

—